Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.52 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239571 | 0.78 | LPAR3 (0.44) | LPAR3LPAR2TSHRMAPTABCC4 | |
| SCHEMBL4950107 | 0.77 | LPAR3 (0.55) | LPAR3LPAR2TSHRMAPTABCC4 | |
| SCHEMBL7902422 | 0.77 | LPAR3 (0.55) | LPAR3LPAR2TSHRMAPTABCC4 | |
| SCHEMBL28333341 | 0.77 | LPAR3 (0.55) | LPAR3LPAR2TSHRMAPTABCC4 | |
| SCHEMBL23630464 | 0.77 | LPAR3 (0.55) | LPAR3LPAR2TSHRMAPTABCC4 | |
| SCHEMBL23630511 | 0.77 | LPAR3 (0.55) | LPAR3LPAR2TSHRMAPTABCC4 | |
| SCHEMBL19307697 | 0.77 | LPAR3 (0.55) | LPAR3LPAR2TSHRMAPTABCC4 | |
| SCHEMBL26828205 | 0.77 | LPAR3 (0.55) | LPAR3LPAR2TSHRMAPTABCC4 | |
| SCHEMBL2961046 | 0.77 | LPAR3 (0.43) | LPAR3LPAR2TSHRMAPTABCC4 | |
| SCHEMBL5955984 | 0.75 | TRPM8 (0.61) | LPAR3LPAR2TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348403-B2 | Peptides and methods for deactivation of organophosphorus-based nerve agents and insecticides | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2008-03-25 | — | — | US | disclosed |
| US-20060216778-A1 | Peptides and methods for deactivation of organophosphorus-based nerve agents and insecticides | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK, THE | 2006-09-28 | — | — | US | disclosed |
| WO-2004052918-A2 | PEPTIDES AND METHODS FOR DEACTIVATION OF ORGANOPHOSPHORUS-BASED NERVE AGENTS AND INSECTICIDES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2004-06-24 | — | — | WO | disclosed |