SCHEMBL19307697

SCHEMBL19307697

C=CCCCCCCCCCCP(=O)(O)O

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 5/20 0.55
LPAR2 Q9HBW0 2/20 0.55
TYMS P04818 1/20 0.50
ABCC4 O15439 1/20 0.46
MAPT P10636 1/20 0.46
LMNA P02545 2/20 0.42
CYP3A4 P08684 1/20 0.42
NFKB1 P19838 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
TSHR P16473 1/20 0.42
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 1/20 0.40
BBOX1 O75936 2/20 0.38
ENPEP Q07075 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28333341 1.00 LPAR3 (0.55) LPAR3LPAR2TYMSABCC4MAPT
SCHEMBL4950107 1.00 LPAR3 (0.55) LPAR3LPAR2TYMSABCC4MAPT
SCHEMBL26828205 1.00 LPAR3 (0.55) LPAR3LPAR2TYMSABCC4MAPT
SCHEMBL23630511 1.00 LPAR3 (0.55) LPAR3LPAR2TYMSABCC4MAPT
SCHEMBL7902422 1.00 LPAR3 (0.55) LPAR3LPAR2TYMSABCC4MAPT
SCHEMBL23630464 1.00 LPAR3 (0.55) LPAR3LPAR2TYMSABCC4MAPT
SCHEMBL4818771 0.98 TYMS (0.52) LPAR3LPAR2TYMSABCC4MAPT
SCHEMBL4821027 0.90
SCHEMBL2960779 0.83 LPAR3 (0.48) LPAR3LPAR2ABCC4MAPTLMNA
SCHEMBL2954618 0.82 LPAR3 (0.52) LPAR3LPAR2ABCC4MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11207260-B2 Phosphonic ethylenic polymer and cosmetic uses thereof L'OREAL (FR) 2021-12-28 US claimed
US-10959935-B2 Hair dyeing process comprising a block polymer bearing phosphonic acid groups and a pigment L'OREAL (FR) 2021-03-30 US claimed
EP-3393429-B1 PHOSPHONIC ETHYLENIC POLYMER AND COSMETIC USES THEREOF OREAL (FR) 2020-11-18 EP claimed
US-20200188282-A1 HAIR DYEING PROCESS COMPRISING A PHOSPHONIC ETHYLENIC POLYMER AND A PIGMENT L'OREAL (FR) 2020-06-18 US claimed
US-20200188283-A1 HAIR DYEING PROCESS COMPRISING A BLOCK POLYMER BEARING PHOSPHONIC ACID GROUPS AND A PIGMENT L'OREAL (FR) 2020-06-18 US claimed
US-10632058-B2 Phosphonic copolymer and use thereof in the cosmetics field L'OREAL (FR) 2020-04-28 US claimed
US-20180369128-A1 BLOCK POLYMER BEARING PHOSPHONIC ACID GROUPS AND COSMETIC USES THEREOF L'OREAL (FR) 2018-12-27 US claimed
US-20180360729-A1 PHOSPHONIC ETHYLENIC POLYMER AND COSMETIC USES THEREOF L'OREAL (FR) 2018-12-20 US claimed
EP-3161026-B1 PHOSPHONIC COPOLYMER AND USE THEREOF IN THE COSMETICS FIELD OREAL (FR) 2018-10-10 EP claimed
US-20170252283-A1 PHOSPHONIC COPOLYMER AND USE THEREOF IN THE COSMETICS FIELD L'OREAL (FR) 2017-09-07 US claimed
US-11207260-B2 Phosphonic ethylenic polymer and cosmetic uses thereof L'OREAL (FR) 2021-12-28 US disclosed
US-10959935-B2 Hair dyeing process comprising a block polymer bearing phosphonic acid groups and a pigment L'OREAL (FR) 2021-03-30 US disclosed
US-10874602-B2 Hair dyeing process comprising a phosphonic ethylenic polymer and a pigment L'OREAL (FR) 2020-12-29 US disclosed
EP-3393429-B1 PHOSPHONIC ETHYLENIC POLYMER AND COSMETIC USES THEREOF OREAL (FR) 2020-11-18 EP disclosed
US-20200188283-A1 HAIR DYEING PROCESS COMPRISING A BLOCK POLYMER BEARING PHOSPHONIC ACID GROUPS AND A PIGMENT L'OREAL (FR) 2020-06-18 US disclosed
US-20200188282-A1 HAIR DYEING PROCESS COMPRISING A PHOSPHONIC ETHYLENIC POLYMER AND A PIGMENT L'OREAL (FR) 2020-06-18 US disclosed
US-10632058-B2 Phosphonic copolymer and use thereof in the cosmetics field L'OREAL (FR) 2020-04-28 US disclosed
US-20180369128-A1 BLOCK POLYMER BEARING PHOSPHONIC ACID GROUPS AND COSMETIC USES THEREOF L'OREAL (FR) 2018-12-27 US disclosed
US-20180360729-A1 PHOSPHONIC ETHYLENIC POLYMER AND COSMETIC USES THEREOF L'OREAL (FR) 2018-12-20 US disclosed
US-20170252283-A1 PHOSPHONIC COPOLYMER AND USE THEREOF IN THE COSMETICS FIELD L'OREAL (FR) 2017-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10959935-B2 Hair dyeing process comprising a block polymer bearing phosphonic acid groups and a pigment GRHPR, MC1R, PHOSPHO1 LPAR3 925/4885LPAR2 1305/4885TYMS 1030/4885
US-20180369128-A1 BLOCK POLYMER BEARING PHOSPHONIC ACID GROUPS AND COSMETIC USES THEREOF TERT, PHOSPHO1, KRT18 LPAR3 546/4885LPAR2 981/4885TYMS 2497/4885
US-11207260-B2 Phosphonic ethylenic polymer and cosmetic uses thereof PHOSPHO1, PKN3, PKN1 LPAR3 1227/4885LPAR2 2176/4885TYMS 2280/4885
US-20200188282-A1 HAIR DYEING PROCESS COMPRISING A PHOSPHONIC ETHYLENIC POLYMER AND A PIGMENT PHOSPHO1, MPHOSPH6, PCNA LPAR3 2367/4885LPAR2 3573/4885TYMS 1291/4885
US-10632058-B2 Phosphonic copolymer and use thereof in the cosmetics field ACP1, PHYKPL, KRT18 LPAR3 2544/4885LPAR2 2919/4885TYMS 1733/4885
US-20200188283-A1 HAIR DYEING PROCESS COMPRISING A BLOCK POLYMER BEARING PHOSPHONIC ACID GROUPS AND A PIGMENT GRHPR, MC1R, PHOSPHO1 LPAR3 925/4885LPAR2 1305/4885TYMS 1030/4885
US-10874602-B2 Hair dyeing process comprising a phosphonic ethylenic polymer and a pigment PHOSPHO1, MPHOSPH6, PCNA LPAR3 2170/4885LPAR2 3420/4885TYMS 1154/4885
US-20180360729-A1 PHOSPHONIC ETHYLENIC POLYMER AND COSMETIC USES THEREOF PHOSPHO1, PKN3, PKN1 LPAR3 1227/4885LPAR2 2176/4885TYMS 2280/4885
US-20170252283-A1 PHOSPHONIC COPOLYMER AND USE THEREOF IN THE COSMETICS FIELD ACP1, PHYKPL, KRT18 LPAR3 2544/4885LPAR2 2919/4885TYMS 1733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.