Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4977288 | 0.91 | MTNR1A (0.45) | MTNR1AMTNR1BTHRATHRB | |
| SCHEMBL4237783 | 0.88 | LMNA (0.47) | MTNR1AMTNR1BKMT2A | |
| SCHEMBL3981848 | 0.87 | MTNR1A (0.48) | MTNR1AMTNR1BKMT2AMAPK1 | |
| SCHEMBL4981179 | 0.86 | MTNR1A (0.46) | MTNR1AMTNR1BPRSS1 | |
| SCHEMBL3976450 | 0.84 | MRGPRX4 (0.43) | HDAC1MTNR1AMTNR1BKMT2ATHRA | |
| SCHEMBL3975780 | 0.83 | MTNR1A (0.53) | HDAC1HDAC2MTNR1AMTNR1BPRSS1 | |
| SCHEMBL3982083 | 0.83 | MTNR1A (0.53) | HDAC1HDAC2MTNR1AMTNR1BPRSS1 | |
| SCHEMBL3978617 | 0.83 | MTNR1A (0.53) | HDAC1HDAC2MTNR1AMTNR1BPRSS1 | |
| SCHEMBL4979327 | 0.83 | FFAR1 (0.46) | HDAC1HDAC2MTNR1AMTNR1B | |
| SCHEMBL3973759 | 0.81 | MTNR1A (0.51) | MTNR1AMTNR1BPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113975-A1 | THIOUREA COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-05-15 | — | — | US | disclosed |
| US-20080096875-A1 | THIOUREA COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096875-A1 | THIOUREA COMPOUNDS | TPMT, HAVCR2, ETV6 | HDAC1 4216/4885HDAC2 4177/4885MTNR1A 4535/4885 |
| US-20080113975-A1 | THIOUREA COMPOUNDS | TPMT, HAVCR2, EIF2AK2 | HDAC1 3829/4885HDAC2 4265/4885MTNR1A 4383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.