Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5461826 | 0.98 | SPHK1 (0.49) | SPHK1CYP4F2CYP4A11SPHK2CA2 | |
| SCHEMBL4985473 | 0.81 | THRA (0.60) | SPHK1SPHK2CA2LMNA | |
| SCHEMBL4980235 | 0.81 | POLB (0.60) | SPHK1CA2LMNA | |
| SCHEMBL242504 | 0.78 | CA2 (0.61) | CYP4F2CYP4A11CA2LMNA | |
| SCHEMBL6534832 | 0.78 | CYP4F2 (0.56) | SPHK1CYP4F2CYP4A11SPHK2CA2 | |
| SCHEMBL23837668 | 0.76 | CA2 (0.63) | CYP4F2CYP4A11CA2LMNA | |
| SCHEMBL4195590 | 0.76 | CA2 (0.63) | CYP4F2CYP4A11CA2LMNA | |
| SCHEMBL3424786 | 0.76 | CA2 (0.63) | CYP4F2CYP4A11CA2LMNA | |
| SCHEMBL9670730 | 0.76 | CA2 (0.63) | CYP4F2CYP4A11CA2LMNA | |
| SCHEMBL31512262 | 0.76 | CA2 (0.63) | CYP4F2CYP4A11CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351743-B1 | Therapeutic guanidines | WYETH (US) | 2008-04-01 | — | — | US | disclosed |
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |
| EP-0751767-A4 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE INC (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0751767-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995020950-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1995-08-10 | — | — | WO | disclosed |