Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | RECQL | P46063 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5610085 | 0.82 | PTK2 (0.38) | PTK2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3250677 | 0.80 | ALDH1A1 (0.59) | PTK2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10636222 | 0.80 | KMT2A (0.35) | PTK2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17837166 | 0.79 | POLB (0.49) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL14744096 | 0.76 | MAPT (0.35) | MAPTALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL31321120 | 0.72 | POLB (0.41) | PTK2MAPTALDH1A1KMT2APOLB | |
| SCHEMBL28523684 | 0.72 | ALDH1A1 (0.35) | PTK2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL30238017 | 0.72 | PTK2 (0.42) | PTK2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4556834 | 0.70 | PRNP (0.45) | PTK2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1286667 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112313229-A | Substituted aminothiazoles as inhibitors of nucleases | 马萨里克大学 | 2021-02-02 | — | — | CN | disclosed |
| WO-2008134036-A1 | ALPHA-SUBSTITUTED ARYLMETHYL PIPERAZINE PYRAZOLO[1,5-α]PYRIMIDINE AMIDE DERIVATIVES | PANACOS PHARMACEUTICALS, INC. (US) | 2008-11-06 | — | — | WO | disclosed |