Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | GLS | O94925 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104106 | 1.00 | HSD17B10 (0.73) | HSD17B10MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL4674015 | 0.86 | MEN1 (0.59) | HSD17B10MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL6246865 | 0.86 | MEN1 (0.59) | HSD17B10MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL6500250 | 0.85 | HSD17B10 (0.67) | HSD17B10MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL4642113 | 0.85 | HSD17B10 (0.67) | HSD17B10MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL30104116 | 0.85 | HSD17B10 (0.67) | HSD17B10MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL3800298 | 0.85 | HSD17B10 (0.67) | HSD17B10MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL30512021 | 0.84 | HSD17B10 (1.00) | HSD17B10MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL504029 | 0.84 | HSD17B10 (1.00) | HSD17B10MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL5743959 | 0.84 | HSD17B10 (0.75) | HSD17B10MEN1KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174800-B | Preparation method of 2, 5-dimethoxy phenylacetic acid | 爱斯特（成都）生物制药股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-112174800-B | Preparation method of 2, 5-dimethoxy phenylacetic acid | 爱斯特（成都）生物制药股份有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-112174800-A | Preparation method of 2, 5-dimethoxy phenylacetic acid | 爱斯特（成都）生物制药股份有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-112174800-A | Preparation method of 2, 5-dimethoxy phenylacetic acid | 爱斯特（成都）生物制药股份有限公司 | 2021-01-05 | — | — | CN | disclosed |
| US-20080119518-A1 | 1-(Piperidin-4- Yl)-1H-Indole Derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| US-20080119518-A1 | 1-(Piperidin-4- Yl)-1H-Indole Derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| US-20080119518-A1 | 1-(Piperidin-4- Yl)-1H-Indole Derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1847535-A1 | 1-(PIPERIDIN-4-YL)-1H-INDOLE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2007-10-24 | — | — | EP | disclosed |
| EP-1847535-A1 | 1-(PIPERIDIN-4-YL)-1H-INDOLE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119518-A1 | 1-(Piperidin-4- Yl)-1H-Indole Derivatives | TPH1, HTR1D, HTR1B | HSD17B10 1696/4885MEN1 1348/4885KMT2A 740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.