SCHEMBL498235

SCHEMBL498235

CSC(C)C1NC(=O)NC1=O

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
BACE1 P56817 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9828518 0.85 TSHR (0.43) TSHRBACE1
SCHEMBL19604178 0.82 TSHR (0.40) TSHRBACE1
SCHEMBL23596518 0.78 TSHR (0.48) TSHRBACE1
SCHEMBL16597503 0.78 TSHR (0.48) TSHRBACE1
SCHEMBL98976 0.78 TSHR (0.48) TSHRBACE1
SCHEMBL9402162 0.76 TSHR (0.46) TSHRBACE1
SCHEMBL9360332 0.74 TSHR (0.44) TSHRBACE1
SCHEMBL9402143 0.74 TSHR (0.44) TSHRBACE1
SCHEMBL9467064 0.72 TSHR (0.43) TSHRBACE1
SCHEMBL6534640 0.71 KDM4E (0.42) TSHRBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109468304-B Hydantoinase mutants 赢创运营有限公司 2022-04-19 CN claimed
US-9957536-B2 Mutants of hydantoinase EVONIK TECHNOCHEMIE GMBH (DE) 2018-05-01 US claimed
EP-2780451-B1 MUTANTS OF HYDANTOINASE EVONIK TECHNOCHEMIE GMBH (DE) 2017-09-20 EP claimed
US-20150056667-A1 MUTANTS OF HYDANTOINASE EVONIK OPERATIONS GMBH (DE) 2015-02-26 US claimed
EP-2780451-A1 MUTANTS OF HYDANTOINASE Evonik Industries AG (DE) 2014-09-24 EP claimed
WO-2013072486-A1 MUTANTS OF HYDANTOINASE EVONIK INDUSTRIES AG (DE) 2013-05-23 WO claimed
CN-109468304-B Hydantoinase mutants 赢创运营有限公司 2022-04-19 CN disclosed
US-10822627-B2 Mutants of hydantoinase EVONIK OPERATIONS GMBH (DE) 2020-11-03 US disclosed
US-20180237814-A1 MUTANTS OF HYDANTOINASE EVONIK TECHNOCHEMIE GMBH (DE) 2018-08-23 US disclosed
US-9957536-B2 Mutants of hydantoinase EVONIK TECHNOCHEMIE GMBH (DE) 2018-05-01 US disclosed
EP-2780451-B1 MUTANTS OF HYDANTOINASE EVONIK TECHNOCHEMIE GMBH (DE) 2017-09-20 EP disclosed
CN-105017111-A Preparation method of methionine sodium CHONGQING UNISPLENDOUR CHEM CO 2015-11-04 CN disclosed
US-20150056667-A1 MUTANTS OF HYDANTOINASE EVONIK OPERATIONS GMBH (DE) 2015-02-26 US disclosed
EP-0210499-B1 PROCESS FOR IMMOBILIZING ENZYMES BASF Aktiengesellschaft (DE) 1991-10-09 EP disclosed
US-4767707-A Immobilization of enzymes with a water-soluble glycidyl ether BASF AKTIENGESELLSCHAFT (DE) 1988-08-30 US disclosed
EP-0046186-B1 METHOD OF PREPARING D-N-CARBAMOYL-ALPHA-AMINO ACIDS, AND MICROORGANISMS THEREFOR BASF Aktiengesellschaft (DE) 1984-05-02 EP disclosed
US-4418146-A CBS 303.80 OR CBS 363.50 THERMOPHILIC, NON-SPORULATING STRAINS BASF AKTIENGESELLSCHAFT (DE) 1983-11-29 US disclosed
EP-0046186-A2 Method of preparing D-N-carbamoyl-alpha-amino acids, and microorganisms therefor BASF Aktiengesellschaft (DE) 1982-02-24 EP disclosed
US-4093444-A Hydantoin derivatives and methods for regulating plant-growth PEPRO, SOCIETE POUR LE DEVELOPPEMENT ET LA VENTE DE SPECIALITES CHIMIQUES (FR) 1978-06-06 US disclosed
US-3990883-A N-(1-carboxy-3-methylthio)propyl urea derivatives and compositions having plant-growth regulating properties PEPRO, SOCIETE POUR LE DEVELOPEMENT ET AL VENTE DE SPECIALITIES CHIMIQUES (FR) 1976-11-09 US disclosed