SCHEMBL4982490

SCHEMBL4982490

CC(C)=CCC/C(C)=C/CNC(=O)CCC(=O)C(N)=O

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FNTA P49354 7/20 0.59
FNTB P49356 5/20 0.59
PGGT1B P53609 3/20 0.57
TRPV1 Q8NER1 6/20 0.56
TRPA1 O75762 1/20 0.52
POLB P06746 1/20 0.47
GGPS1 O95749 2/20 0.45
FDPS P14324 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1723041 0.89 FNTA (0.71) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL1722741 0.89 FNTA (0.71) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL1724882 0.86 FNTA (0.61) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL1724883 0.86 FNTA (0.61) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL16770097 0.84 FNTA (0.66) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL15161516 0.83 FNTA (0.64) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL10603862 0.81 FNTA (0.67) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL8940673 0.81 FNTA (0.67) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL10605679 0.81 FNTA (0.67) FNTAFNTBPGGT1BTRPV1TRPA1
SCHEMBL8940669 0.81 FNTA (0.67) FNTAFNTBPGGT1BTRPV1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080119556-A1 Geranly compounds AKIYAMA KIYOSHI 2008-05-22 US disclosed
US-20080113939-A1 Geranyl compounds AKIYAMA KIYOSHI 2008-05-15 US disclosed
US-20050119474-A1 Geranyl compounds OHGEN RESEARCH LABORATORIES, LTD. (JP) 2005-06-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080113939-A1 Geranyl compounds GGPS1, FNTA, CCNE2 FNTA 2/4885FNTB 64/4885PGGT1B 30/4885
US-20080119556-A1 Geranly compounds GMNN, TP53, MCL1 FNTA 406/4885FNTB 1727/4885PGGT1B 470/4885
US-20050119474-A1 Geranyl compounds GGPS1, FNTA, CCNE2 FNTA 2/4885FNTB 64/4885PGGT1B 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.