Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990242 | 0.78 | SLC6A2 (0.51) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| Mandelic Acid SCHEMBL3893473 | 0.77 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL19775842 | 0.69 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL4288613 | 0.69 | SLC6A2 (0.55) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL2235604 | 0.69 | SLC6A2 (0.55) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL8254519 | 0.69 | SLC6A2 (0.55) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL3363271 | 0.68 | SLC6A2 (0.48) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5348264 | 0.68 | SLC6A2 (0.53) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| Sertraline SCHEMBL6442186 | 0.67 | SLC6A4 (0.62) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL8814001 | 0.67 | SLC6A2 (0.55) | SLC6A4SLC6A2SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080114071-A1 | Processes for preparing sertraline | TEVA PHARMACEUTICALS USA, INC. | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114071-A1 | Processes for preparing sertraline | HTR5A, HTR1A, SLC6A4 | SLC6A4 3/4885SLC6A2 14/4885SLC6A3 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.