SCHEMBL498322

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29471988	0.84	EGFR (0.56)	CA12CA1CA2CA9CA14
	SCHEMBL22532474	0.84	EGFR (0.56)	CA12CA1CA2CA9CA14
	SCHEMBL497642	0.84	CA1 (0.61)	CA12CA1CA2CA9CA14
	SCHEMBL497983	0.83	HSD17B1 (0.69)	CA12CA1CA2CA9CA14
	SCHEMBL22532196	0.81	EGFR (0.52)	CA12CA1CA2CA9CA14
	SCHEMBL29471965	0.81	EGFR (0.52)	CA12CA1CA2CA9CA14
	SCHEMBL497922	0.81	CA12 (0.58)	CA12CA1CA2CA9CA14
	SCHEMBL497995	0.81	HSD17B1 (0.58)	CA12CA1CA2CA9CA14
	SCHEMBL23226530	0.80	NOTUM (0.54)	CA12CA1CA2CA9CA14
	SCHEMBL22531730	0.80	NOTUM (0.50)	CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.