SCHEMBL10940484

SCHEMBL10940484

N[C@@H](CC(=O)OC(=O)[C@@H]1CCCN1)C(=O)OC(=O)[C@@H](N)Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSC P53634 2/20 0.45
TYR P14679 1/20 0.41
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39
ALPI P09923 1/20 0.39
PKM P14618 1/20 0.39
PTGS1 P23219 1/20 0.39
XIAP P98170 1/20 0.39
SLC7A5 Q01650 1/20 0.39
DPP4 P27487 3/20 0.39
DPP8 Q6V1X1 2/20 0.39
DPP9 Q86TI2 2/20 0.39
DPP7 Q9UHL4 2/20 0.39
SLC15A1 P46059 2/20 0.38
REN P00797 1/20 0.37
FAP Q12884 1/20 0.37
ELANE P08246 1/20 0.37
TSHR P16473 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3726266 0.91 CTSC (0.50) CTSCTYRHTR2CHTR2BALPI
SCHEMBL2478803 0.91 CTSC (0.50) CTSCTYRHTR2CHTR2BALPI
SCHEMBL498386 0.91 CTSC (0.50) CTSCTYRHTR2CHTR2BALPI
SCHEMBL10757105 0.84 HTR2C (0.45) CTSCTYRHTR2CHTR2BALPI
SCHEMBL3489282 0.83 NOS2 (0.35) DPP4DPP8DPP9DPP7FAP
Tyrosine SCHEMBL9686139 0.83 SLC7A5 (0.50) CTSCTYRHTR2CHTR2BALPI
SCHEMBL11561585 0.83 CTSC (0.49) CTSCHTR2CHTR2BSLC15A1ELANE
SCHEMBL4205064 0.81 SLC7A5 (0.44) CTSCTYRHTR2CHTR2BSLC7A5
SCHEMBL4778519 0.79 SLC7A5 (0.56) CTSCTYRALPIPKMPTGS1
Phenylalanine SCHEMBL5672080 0.79 SLC7A5 (0.51) CTSCTYRHTR2CHTR2BALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4550082-A NUCLEAR MAGNETIC RESONANCE; SPECTRUM ANALYSIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1985-10-29 US claimed