⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19735715 | 0.78 | CA1 (0.39) | — | |
| SCHEMBL1043863 | 0.76 | CA1 (0.41) | — | |
| SCHEMBL5493918 | 0.75 | CA1 (0.41) | — | |
| SCHEMBL8074102 | 0.75 | — | — | |
| SCHEMBL9422838 | 0.75 | — | — | |
| SCHEMBL2085247 | 0.74 | CA2 (0.41) | — | |
| SCHEMBL47322 | 0.74 | CA2 (0.43) | — | |
| SCHEMBL6343831 | 0.74 | CA2 (0.43) | — | |
| SCHEMBL29171767 | 0.72 | CA2 (0.42) | — | |
| Ammonia Solution, Strong SCHEMBL12506223 | 0.72 | CA2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080114020-A1 | such as 7,7-Difluoro-2,3-dimethyl-8-hydroxy-9-phenyl-7H-8,9-dihydro-pyrano(2,3-c]imidazo[1,2-a]pyridine; inhibit gastric acid secretion by blockade of the H+/K+-ATPase; reversible proton pump inhibitors (rPPI's) or acid pump antagonists (APA's) bind reversibly to H+/K+-ATPase; gastrointestinal disorders | ALTANA PHARMA AG (DE) | 2008-05-15 | — | — | US | disclosed |
| CN-101035793-A | Difluoro-substituted imidazopyridines | ALTANA PHARMA AG (DE) | 2007-09-12 | — | — | CN | disclosed |
| EP-1802629-A1 | DIFLUORO-SUBSTITUTED IMIDAZOPYRIDINES | Altana Pharma AG (DE) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040338-A1 | DIFLUORO-SUBSTITUTED IMIDAZOPYRIDINES | ALTANA PHARMA AG (DE) | 2006-04-20 | — | — | WO | disclosed |
| EP-0974601-B1 | Olefin polymerization catalyst and process for producing olefin polymer | JAPAN POLYCHEM CORP (JP) | 2003-09-10 | — | — | EP | disclosed |
| CN-1244868-A | Novel carbapenem derivative | MEIJI SEIKA KAISHA (JP) | 2000-02-16 | — | — | CN | disclosed |
| EP-0974601-A2 | Olefin polymerization catalyst and process for producing olefin polymer | Japan Polychem Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |