Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 9/20 | 0.52 |
| ▸ | CSF1R | P07333 | 8/20 | 0.52 |
| ▸ | FLT3 | P36888 | 6/20 | 0.52 |
| ▸ | KDR | P35968 | 5/20 | 0.52 |
| ▸ | MET | P08581 | 11/20 | 0.51 |
| ▸ | FLT4 | P35916 | 2/20 | 0.48 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4655552 | 0.91 | PDGFRB (0.53) | PDGFRBCSF1RFLT3KDRMET | |
| SCHEMBL4513314 | 0.81 | PDGFRB (0.65) | PDGFRBCSF1RFLT3KDRMET | |
| SCHEMBL4500994 | 0.81 | PDGFRB (0.71) | PDGFRBCSF1RFLT3KDRMET | |
| SCHEMBL4504727 | 0.80 | MET (0.54) | PDGFRBCSF1RFLT3KDRMET | |
| SCHEMBL4560215 | 0.79 | PDGFRB (0.66) | PDGFRBCSF1RFLT3KDRMET | |
| SCHEMBL4503473 | 0.78 | PDGFRB (0.84) | PDGFRBCSF1RFLT3KDRMET | |
| SCHEMBL4514191 | 0.77 | MET (0.50) | PDGFRBCSF1RFLT3KDRMET | |
| SCHEMBL4220960 | 0.72 | PDGFRB (0.60) | PDGFRBCSF1RFLT3KDRMET | |
| SCHEMBL2173338 | 0.72 | PDGFRB (0.70) | PDGFRBCSF1RFLT3KDRMET | |
| SCHEMBL4514736 | 0.71 | PDGFRB (0.83) | PDGFRBCSF1RFLT3KDRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994024-A2 | QUINOLINE DERIVATIVES | AstraZeneca AB (SE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007099323-A2 | QUINOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-09-07 | — | — | WO | disclosed |