Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | C5 | P01031 | 2/20 | 0.52 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5457346 | 0.99 | FAAH (0.57) | FAAHMAPTHSD17B10HTTMEN1 | |
| SCHEMBL4983901 | 0.82 | MAPT (0.48) | FAAHMAPTHSD17B10HTTMEN1 | |
| SCHEMBL22502142 | 0.80 | C5 (0.65) | FAAHMAPTHSD17B10HTTMEN1 | |
| Oxalic Acid SCHEMBL4981838 | 0.78 | MAPT (0.49) | FAAHMAPTHSD17B10HTTMEN1 | |
| SCHEMBL4983215 | 0.76 | PTGES (0.56) | FAAHGAALMNA | |
| SCHEMBL19476963 | 0.75 | EHMT2 (0.56) | — | |
| Bromide SCHEMBL5458791 | 0.74 | PTGES (0.55) | FAAHGAALMNA | |
| SCHEMBL18784001 | 0.74 | CA12 (0.63) | MAPTHTTMEN1KMT2ASMPD1 | |
| SCHEMBL6588516 | 0.73 | SMPD1 (0.64) | FAAHMEN1KMT2ASMPD1PDE4A | |
| SCHEMBL10789734 | 0.73 | KMT2A (0.56) | MAPTMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351743-B1 | Therapeutic guanidines | WYETH (US) | 2008-04-01 | — | — | US | disclosed |
| EP-0751767-A4 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE INC (US) | 1997-12-10 | — | — | EP | disclosed |
| EP-0751767-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995020950-A1 | THERAPEUTIC GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1995-08-10 | — | — | WO | disclosed |