Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200114 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL8199056 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL8199934 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL2167960 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL2167102 | 0.98 | CYP1A2 (0.52) | CYP1A2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL498505 | 0.94 | NPC1 (0.50) | CYP1A2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL96245 | 0.86 | MEN1 (0.54) | CYP1A2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL9466506 | 0.84 | MEN1 (0.52) | CYP1A2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL7529684 | 0.82 | NPC1 (0.50) | CYP1A2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL28879045 | 0.82 | NPC1 (0.50) | CYP1A2CYP2C19NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253194-B2 | Compounds and inhibitors of phospholipases | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-08-07 | — | — | US | claimed |
| EP-1309552-A4 | COMPOUNDS AND INHIBITORS OF PHOSPHOLIPASES | UNIV QUEENSLAND (AU) | 2005-07-20 | — | — | EP | claimed |
| US-20040033995-A1 | Compounds and inhibitors of phospholipases | QUEENSLAND, THE UNIVERSITY OF (AU) | 2004-02-19 | — | — | US | claimed |
| JP-2004503604-A | — | — | 2004-02-05 | — | — | JP | claimed |
| EP-1309552-A1 | COMPOUNDS AND INHIBITORS OF PHOSPHOLIPASES | THE UNIVERSITY OF QUEENSLAND (AU) | 2003-05-14 | — | — | EP | claimed |
| WO-2002008189-A1 | COMPOUNDS AND INHIBITORS OF PHOSPHOLIPASES | THE UNIVERSITY OF QUEENSLAND (AU) | 2002-01-31 | — | — | WO | claimed |
| EP-0503426-B1 | Quinone derivatives | EISAI CO LTD (JP) | 1996-12-27 | — | — | EP | claimed |
| US-5329010-A | Unsaturated groups with heteroarylalkyl groups and carboxy derivatives | EISAI CO., LTD. (JP) | 1994-07-12 | — | — | US | claimed |
| EP-0503426-A1 | Quinone derivatives | Eisai Co., Ltd. (JP) | 1992-09-16 | — | — | EP | claimed |
| US-10190009-B2 | Ink composition, ink jet recording method using same, and colored material | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2019-01-29 | — | — | US | disclosed |
| EP-2853587-B1 | Method for isolating cells | MERCK PATENT GMBH (DE) | 2017-10-11 | — | — | EP | disclosed |
| US-9518068-B2 | Compounds containing hydrido-tricyano-borate anions | MERCK PATENT GMBH (DE) | 2016-12-13 | — | — | US | disclosed |
| EP-2714698-B1 | COMPOUNDS CONTAINING HYDRIDO-TRICYANO-BORATE ANIONS | MERCK PATENT GMBH (DE) | 2016-11-09 | — | — | EP | disclosed |
| US-9409925-B2 | Compounds containing hydrido-tricyano-borate anions | MERCK PATENT GMBH (DE) | 2016-08-09 | — | — | US | disclosed |
| US-5329010-A | Unsaturated groups with heteroarylalkyl groups and carboxy derivatives | EISAI CO., LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0503426-A1 | Quinone derivatives | Eisai Co., Ltd. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4883800-A | DIABETES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-11-28 | — | — | US | disclosed |
| US-4734419-A | Quinazoline derivatives, compositions thereof and their use in treating diabetic complications | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0218999-A2 | New quinazoline derivatives, process for their production and pharmaceutical compositions comprising them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| US-4477447-A | ANTIBIOTIC, BACTERICIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040033995-A1 | Compounds and inhibitors of phospholipases | PLA2G4C, PLA2G4B, PLA2G4A | CYP1A2 2230/4885CYP2C19 2381/4885NPC1 2383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.