Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12544321 | 0.81 | TSHR (0.62) | ALDH1A1ALOX15MAPK1TSHRKMT2A | |
| SCHEMBL10464829 | 0.79 | TSHR (0.67) | ALDH1A1TSHRKMT2AESR1CHRM3 | |
| SCHEMBL4982858 | 0.79 | MAPK1 (0.44) | ALDH1A1ALOX15MAPK1TSHRKMT2A | |
| SCHEMBL12556878 | 0.77 | TSHR (0.51) | ALDH1A1ALOX15TSHRKMT2ACYP3A4 | |
| SCHEMBL7470898 | 0.76 | GAA (0.46) | ALDH1A1TSHRKMT2ACYP3A4ESR1 | |
| SCHEMBL9040920 | 0.75 | GAA (0.32) | GAA | |
| SCHEMBL13008873 | 0.74 | SLC6A2 (0.38) | ALOX15MAPK1TSHRKMT2ACHRM3 | |
| SCHEMBL7473648 | 0.74 | GAA (0.31) | GAA | |
| SCHEMBL6809943 | 0.72 | KMT2A (0.37) | ALOX15TSHRKMT2A | |
| SCHEMBL12589187 | 0.71 | ALDH1A1 (0.37) | ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388052-B2 | Process for the preparation of block copolymers | POLIMERI EUROPA S.P.A. (IT) | 2008-06-17 | — | — | US | disclosed |
| EP-1519970-B1 | PROCESS FOR THE PREPARATION OF BLOCK COPOLYMERS | POLIMERI EUROPA SPA (IT) | 2007-10-24 | — | — | EP | disclosed |
| US-20070219329-A1 | polymerizing styrene using a nitroxy free radical catalyst, then adding methacrylonitrile; 2-methyl-2-(2,2,6,6-tetramethylpiperidin-1-yloxy)propionitrile catalyst; | POLIMERI EUROPA S.P.A. (IT) | 2007-09-20 | — | — | US | disclosed |