Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 6/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.61 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.51 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97498 | 0.88 | CA2 (0.67) | CA2CA1NAALAD2FOLH1CA12 | |
| SCHEMBL698067 | 0.88 | CA2 (0.67) | CA2CA1NAALAD2FOLH1CA12 | |
| SCHEMBL715646 | 0.88 | CA2 (0.67) | CA2CA1NAALAD2FOLH1CA12 | |
| SCHEMBL27564186 | 0.88 | CA2 (0.75) | CA2CA1NAALAD2FOLH1CA12 | |
| SCHEMBL2252322 | 0.87 | CA2 (0.66) | CA2CA1NAALAD2FOLH1CA12 | |
| SCHEMBL8237305 | 0.87 | CA2 (0.66) | CA2CA1NAALAD2FOLH1CA12 | |
| SCHEMBL4618531 | 0.86 | CA2 (0.65) | CA2CA1NAALAD2FOLH1CA12 | |
| SCHEMBL28287497 | 0.86 | CA2 (0.65) | CA2CA1NAALAD2FOLH1CA12 | |
| Ammonia Solution, Strong SCHEMBL28375957 | 0.86 | CA2 (0.65) | CA2CA1NAALAD2FOLH1CA12 | |
| SCHEMBL28184998 | 0.86 | CA2 (0.65) | CA2CA1NAALAD2FOLH1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101611008-A | C3A receptor modulators and methods of use thereof | ENCYSIVE PHARMACEUTICALS INC (US) | 2009-12-23 | — | — | CN | disclosed |
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | C3AR1 1/4885CA2 3182/4885CA1 3413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.