Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3966419 | 0.88 | TRPV1 (1.00) | TRPV1MAPK3 | |
| SCHEMBL4993937 | 0.87 | TRPV1 (0.60) | TRPV1MAPK3 | |
| SCHEMBL4353560 | 0.86 | TRPV1 (1.00) | TRPV1MAPK3 | |
| SCHEMBL1863478 | 0.84 | TRPV1 (0.74) | TRPV1MAPK3 | |
| SCHEMBL4991257 | 0.83 | TRPV1 (0.60) | TRPV1MAPK3 | |
| SCHEMBL1867152 | 0.82 | TRPV1 (0.70) | TRPV1MAPK3 | |
| SCHEMBL1860822 | 0.82 | TRPV1 (0.70) | TRPV1MAPK3 | |
| SCHEMBL1859378 | 0.81 | TRPV1 (0.73) | TRPV1MAPK3 | |
| SCHEMBL1856817 | 0.81 | TRPV1 (0.69) | TRPV1MAPK3 | |
| SCHEMBL5127607 | 0.79 | TRPV1 (0.67) | TRPV1MAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080175794-A1 | Substituted Pyridazinyl- and Pyrimidinyl-Quinolin-4-Ylamine Analogues | NEUROGEN CORPORATION (US) | 2008-07-24 | — | — | US | disclosed |
| US-20080175794-A1 | Substituted Pyridazinyl- and Pyrimidinyl-Quinolin-4-Ylamine Analogues | NEUROGEN CORPORATION (US) | 2008-07-24 | — | — | US | disclosed |
| US-20080175794-A1 | Substituted Pyridazinyl- and Pyrimidinyl-Quinolin-4-Ylamine Analogues | NEUROGEN CORPORATION (US) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080175794-A1 | Substituted Pyridazinyl- and Pyrimidinyl-Quinolin-4-Ylamine Analogues | PIGS, HRH4, GPR68 | TRPV1 199/4885MAPK3 2900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.