⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329454 | 0.80 | TSHR (0.43) | — | |
| SCHEMBL1444752 | 0.79 | TSHR (0.52) | — | |
| SCHEMBL1312250 | 0.79 | CYP3A4 (0.43) | — | |
| SCHEMBL8384 | 0.78 | TSHR (0.35) | — | |
| SCHEMBL1698298 | 0.77 | TSHR (0.39) | — | |
| SCHEMBL11416944 | 0.77 | MYC (0.48) | — | |
| SCHEMBL19875811 | 0.77 | TSHR (0.62) | — | |
| SCHEMBL3644208 | 0.77 | TSHR (0.62) | — | |
| SCHEMBL30666154 | 0.77 | TSHR (0.62) | — | |
| SCHEMBL1141159 | 0.77 | TSHR (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3915 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399212-A1 | SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES | Bayer Aktiengesellschaft (DE) | 2024-07-17 | — | — | EP | claimed |
| US-20240209026-A1 | A4B7 THIOETHER PEPTIDE DIMER ANTAGONISTS | PROTAGONIST THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | US | claimed |
| CN-118159542-A | Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents | 拜耳公司 | 2024-06-07 | — | — | CN | claimed |
| CN-117945876-A | Benzophenone compound and preparation method and application thereof | 湖北理工学院 | 2024-04-30 | — | — | CN | claimed |
| CN-116063666-B | Multifunctional polyester material and preparation method and application thereof | 四川大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117903168-A | Pyrrolo [2,3-d ] thiazole derivatives, and preparation method and application thereof | 南开大学 | 2024-04-19 | — | — | CN | claimed |
| CN-117820163-A | Synthesis method of trifloxystrobin | 山东华阳农药化工集团有限公司 | 2024-04-05 | — | — | CN | claimed |
| CN-114751860-B | Synthesis method of nuciferine or nuciferine derivative, nuciferine derivative and application of nuciferine derivative | 华侨大学 | 2024-03-15 | — | — | CN | claimed |
| EP-4327881-A2 | PROCESSES FOR THE PREPARATION OF GLASDEGIB AND SALT THEREOF AND SOLID STATE FORMS OF GLASDEGIB MALEATE AND PROCESS FOR PREPARATION THEREOF | Assia Chemical Industries LTD (IL) | 2024-02-28 | — | — | EP | claimed |
| US-20240033318-A1 | PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION | OHIO STATE INNOVATION FOUNDATION | 2024-02-01 | — | — | US | claimed |
| US-4113872-A | DIURETICS, SALURETICS, ANTIHYPERTENSIVE, ANTITHROMBOTIC AGENTS | BAKER AKTIENGESELLSHAFT (DE) | 1978-09-12 | — | — | US | claimed |
| US-4112109-A | DIURETIC, SALURETIC, ANTIHYPERTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-09-05 | — | — | US | claimed |
| US-4099011-A | DIURETIC, SALURETIC, HYPOTENSIVE, ANTITHROMBOTIC | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | claimed |
| US-4087444-A | Amides as ovulation inhibitors | ELI LILLY AND COMPANY (US) | 1978-05-02 | — | — | US | claimed |
| US-4068085-A | YELLOW AND RED ON POLYESTERS AND ACRYLICS | CIBA-GEIGY CORPORATION (US) | 1978-01-10 | — | — | US | claimed |
| US-4066637-A | BASIC DIAMINOPYRIDINE-(3)-AZO DYESTUFFS | CIBA-GEIGY CORPORATION (US) | 1978-01-03 | — | — | US | claimed |
| US-4006163-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1977-02-01 | — | — | US | claimed |
| US-3988345-A | HYPOTENSIVE AGENTS; PHOSPHORUS OXYCHLORIDE | CHEMIE LINZ AKTIENGESELLSCHAFT (OE) | 1976-10-26 | — | — | US | claimed |
| US-3943120-A | WATER INSOLUBLE | CIBA-GEIGY AG (CH) | 1976-03-09 | — | — | US | claimed |
| US-3933785-A | Azo compounds | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | claimed |