Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11414350 | 0.85 | TSHR (0.39) | TSHRACHESMN1; SMN2MYCCYP1A2 | |
| SCHEMBL6281274 | 0.85 | MEN1 (0.40) | TSHRNPC1RAB9ASMN1; SMN2CA1 | |
| SCHEMBL11416944 | 0.83 | MYC (0.48) | TSHRACHENPC1CASP3RAB9A | |
| SCHEMBL11416939 | 0.82 | ELANE (0.46) | NPC1HPGDLRRK2GAACYP1A2 | |
| SCHEMBL49876 | 0.80 | — | — | |
| SCHEMBL160151 | 0.78 | TSHR (0.45) | TSHRBRD4ACHENPC1CASP3 | |
| SCHEMBL29703355 | 0.78 | TSHR (0.45) | TSHRBRD4ACHENPC1CASP3 | |
| SCHEMBL29385200 | 0.78 | TSHR (0.45) | TSHRBRD4ACHENPC1CASP3 | |
| SCHEMBL28586997 | 0.78 | TSHR (0.45) | TSHRBRD4ACHENPC1CASP3 | |
| SCHEMBL1472952 | 0.77 | TSHR (0.67) | TSHRACHENPC1CASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7182934-B2 | Ultrasonic contrast agents; aqueous suspension | GE HEALTHCARE AS (NO) | 2007-02-27 | — | — | US | disclosed |
| EP-0971747-B1 | CONTRAST AGENTS | AMERSHAM HEALTH AS (NO) | 2005-12-28 | — | — | EP | disclosed |
| US-20050201930-A1 | Contrast agents | GE HEALTHCARE AS (NO) | 2005-09-15 | — | — | US | disclosed |
| US-6921525-B2 | Contrast agents | AMERSHAM HEALTH AS (NO) | 2005-07-26 | — | — | US | disclosed |
| US-20030228254-A1 | Diagnosis of cardiovascular disorders | AMERSHAM HEALTH AS (NO) | 2003-12-11 | — | — | US | disclosed |
| US-6524552-B2 | Imaging cardiovascular disorders | GE HEALTHCARE AS (NO) | 2003-02-25 | — | — | US | disclosed |
| US-20010016587-A1 | Contrast agents | NYCOMED IMAGING AS | 2001-08-23 | — | — | US | disclosed |
| US-6264914-B1 | CONTAINING IMIDAZOLE RING | NYCOMED IMAGING AS (NO) | 2001-07-24 | — | — | US | disclosed |
| EP-0971747-A2 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998018496-A2 | CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1998-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030228254-A1 | Diagnosis of cardiovascular disorders | AGTR1, AGTR2, AGT | TSHR 166/4885BRD4 3723/4885ACHE 3557/4885 |
| US-20010016587-A1 | Contrast agents | AGTR1, AGTR2, VIPR1 | TSHR 120/4885BRD4 3050/4885ACHE 3127/4885 |
| US-20050201930-A1 | Contrast agents | AGTR1, AGTR2, VIPR1 | TSHR 149/4885BRD4 2521/4885ACHE 3182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.