Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL27722481 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acrylic Acid SCHEMBL18114676 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acrylic Acid SCHEMBL740134 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acrylic Acid SCHEMBL28865161 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acrylic Acid SCHEMBL28608537 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acrylic Acid SCHEMBL8997498 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acrylic Acid SCHEMBL701228 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acrylic Acid SCHEMBL2524151 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acrylic Acid SCHEMBL301603 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 | |
| Acrylic Acid SCHEMBL11137999 | 0.92 | ALDH1A1 (0.52) | ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782599-B1 | DENTAL POLYMERIZABLE COMPOSITION BASED ON CONDENSED SILANES | VOCO GMBH (DE) | 2025-09-17 | — | — | EP | claimed |
| EP-3328342-B1 | DENTAL ADHESIVE | DENTSPLY DETREY GMBH (DE) | 2025-01-29 | — | — | EP | claimed |
| CN-114096092-B | Electronic equipment shell, preparation method thereof and electronic equipment | OPPO广东移动通信有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-118512332-A | Application of acrylamide monomer in dental adhesive and dental adhesive | 桂林凯文彼德科技有限公司 | 2024-08-20 | — | — | CN | claimed |
| US-11998409-B2 | Dental composite blank and method for manufacturing same | VERICOM CO., LTD. (KR) | 2024-06-04 | — | — | US | claimed |
| CN-116421476-A | Dental cement composition and method of use | 泽斯特知识产权控股有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-110719767-B | Dental cement composition and method of use | 泽斯特知识产权控股有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-110693722-B | Resin material for nanometer tooth carving | 河南豫兰贵人实业有限公司 | 2022-07-05 | — | — | CN | claimed |
| WO-2022088519-A1 | DENTAL BONDING PRE-TREATMENT SYSTEM BASED ON COPPER AND ZINC IONS AND USE THEREOF | 浙江大学 | 2022-05-05 | — | — | WO | claimed |
| CN-112336633-B | Dental bonding pretreatment system based on copper and zinc ions and application | 浙江大学 | 2022-03-22 | — | — | CN | claimed |
| WO-1998046198-A1 | DENTAL PRIMER COMPOSITIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-10-22 | — | — | WO | claimed |
| WO-1998019650-A1 | DENTAL COMPOSITION SYSTEM AND METHOD | DENTSPLY INTERNATIONAL INC. (US) | 1998-05-14 | — | — | WO | claimed |
| US-5367002-A | Polyalkenoic acid, elutable glass filler | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1994-11-22 | — | — | US | claimed |
| EP-0321683-B1 | Adhesive composition which bonds to collagen and calcium | DENTSPLY INT INC (US) | 1994-01-19 | — | — | EP | claimed |
| EP-0554890-A1 | Dental composition and method | DENTSPLY INTERNATIONAL, INC. (US) | 1993-08-11 | — | — | EP | claimed |
| EP-0356868-A2 | A method of treating a tooth with adhesive dental cavity basing composition | DENTSPLY INTERNATIONAL, INC. (US) | 1990-03-07 | — | — | EP | claimed |
| US-4814423-A | TEETH, FILLINGS, UNSATURATED PHOSPHATES | DENTSPLY RESEARCH & DEVELOPMENT CORP. (US) | 1989-03-21 | — | — | US | claimed |
| EP-0088527-B1 | ADHESION PROMOTERS | Dentsply Research and Development Corporation (US) | 1987-07-22 | — | — | EP | claimed |
| US-4514342-A | ADHESION PROMOTERS; DENTISTRY | DENTSPLY LIMITED (GB) | 1985-04-30 | — | — | US | claimed |
| EP-0088527-A2 | Adhesion promoters | Dentsply Research and Development Corporation (US) | 1983-09-14 | — | — | EP | claimed |