Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985093 | 0.87 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL4993433 | 0.87 | P2RX7 (0.48) | P2RX7 | |
| SCHEMBL4989574 | 0.84 | MEN1 (0.48) | P2RX7EPHX2 | |
| SCHEMBL4986230 | 0.82 | P2RX7 (0.51) | P2RX7 | |
| SCHEMBL4984930 | 0.82 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL4986745 | 0.81 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL4991240 | 0.80 | P2RX7 (0.41) | P2RX7 | |
| SCHEMBL4985382 | 0.80 | P2RX7 (0.62) | P2RX7 | |
| SCHEMBL14272319 | 0.78 | TSHR (0.49) | P2RX7EPHX2 | |
| SCHEMBL4984815 | 0.77 | GRM5 (0.48) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080039478-A1 | Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof | RENOVIS, INC. | 2008-02-14 | — | — | US | claimed |
| US-7297700-B2 | Bicycloheteroaryl compounds as P2X7 modulators and uses thereof | RENOVIS, INC. (US) | 2007-11-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039478-A1 | Bicycloheteroaryl Compounds as P2X7 Modulators and Uses Thereof | P2RX7, P2RX3, P2RX2 | P2RX7 1/4885EPHX2 569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.