Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905506 | 0.87 | ALOX5 (0.38) | ALOX5F2RL1EPHX1POLBPKM | |
| SCHEMBL1905412 | 0.82 | ALOX5 (0.38) | ALOX5F2RL1EPHX1POLB | |
| SCHEMBL4997042 | 0.75 | GRIN2D (0.33) | ALOX5F2RL1EPHX1 | |
| SCHEMBL17294254 | 0.74 | CA1 (0.45) | ALOX5EPHX1TSHR | |
| SCHEMBL28114164 | 0.74 | THRB (0.39) | ALOX5EPHX1 | |
| SCHEMBL9680319 | 0.73 | CHRM1 (0.32) | — | |
| SCHEMBL23748750 | 0.72 | EPHX1 (0.48) | ALOX5EPHX1TSHR | |
| SCHEMBL28386491 | 0.72 | EPHX1 (0.48) | ALOX5EPHX1TSHR | |
| SCHEMBL6270156 | 0.72 | EPHX1 (0.48) | ALOX5EPHX1TSHR | |
| SCHEMBL15774888 | 0.72 | EPHX1 (0.48) | ALOX5EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987019-A1 | BENZOYL-PIPERIDINE DERIVATIVES AS 5HT2/D3 MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093540-A1 | BENZOYL-PIPERIDINE DERIVATIVES AS 5HT2/D3 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-23 | — | — | WO | disclosed |