Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA4 | P22748 | 5/20 | 0.38 |
| ▸ | CA6 | P23280 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370 | 0.80 | ALDH1A1 (0.39) | CA1CA2CA4CA6NPC1 | |
| SCHEMBL18224272 | 0.78 | NOS1 (0.45) | CA1CA2CA4CA6NPC1 | |
| SCHEMBL24829920 | 0.78 | NOS1 (0.45) | CA1CA2CA4CA6NPC1 | |
| SCHEMBL27953389 | 0.76 | KMT2A (0.44) | CA1CA2CA4CA6NPC1 | |
| SCHEMBL24433004 | 0.76 | KMT2A (0.44) | CA1CA2CA4CA6NPC1 | |
| SCHEMBL27942666 | 0.76 | KMT2A (0.44) | CA1CA2CA4CA6NPC1 | |
| SCHEMBL1134441 | 0.75 | CA1 (0.41) | CA1CA2CA4CA6NPC1 | |
| SCHEMBL3437946 | 0.73 | CA1 (0.49) | CA1CA2CA4CA6NPC1 | |
| SCHEMBL23374493 | 0.69 | NPC1 (0.45) | CA1CA2CA4CA6NPC1 | |
| SCHEMBL1134400 | 0.69 | CA1 (0.42) | CA1CA2CA4CA6NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378232-B2 | Assay for melanogenesis | NEW YORK UNIVERSITY (US) | 2008-05-27 | — | — | US | disclosed |
| EP-1501928-A4 | ASSAY FOR MELANOGENESIS | UNIV NEW YORK (US) | 2007-08-15 | — | — | EP | disclosed |
| EP-1501928-A1 | ASSAY FOR MELANOGENESIS | NEW YORK UNIVERSITY (US) | 2005-02-02 | — | — | EP | disclosed |
| US-20040038328-A1 | Assay for melanogenesis | NEW YORK UNIVERSITY | 2004-02-26 | — | — | US | disclosed |
| WO-2003095645-A1 | ASSAY FOR MELANOGENESIS | NEW YORK UNIVERSITY (US) | 2003-11-20 | — | — | WO | disclosed |