Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498864 | 1.00 | REN (0.44) | RENCYP3A4 | |
| SCHEMBL498863 | 1.00 | REN (0.44) | RENCYP3A4 | |
| SCHEMBL3336471 | 0.92 | REN (0.48) | RENCYP3A4 | |
| SCHEMBL3335146 | 0.92 | REN (0.48) | RENCYP3A4 | |
| SCHEMBL3336109 | 0.92 | REN (0.48) | RENCYP3A4 | |
| SCHEMBL498881 | 0.91 | REN (0.41) | RENCYP3A4 | |
| SCHEMBL499139 | 0.91 | REN (0.41) | RENCYP3A4 | |
| SCHEMBL499177 | 0.90 | REN (0.45) | RENCYP3A4 | |
| SCHEMBL10253605 | 0.90 | REN (0.55) | RENCYP3A4 | |
| SCHEMBL8074950 | 0.90 | REN (0.55) | RENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106221-B2 | Renin inhibitors | VITAE PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | claimed |
| US-8106221-B2 | Renin inhibitors | VITAE PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |