Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ACP3 | P15309 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4994828 | 0.87 | ACP3 (0.61) | TDP1ACP3FFAR1AKR1B1CYP1A2 | |
| SCHEMBL5053304 | 0.82 | GRM3 (0.51) | — | |
| SCHEMBL4988468 | 0.81 | CDYL (0.52) | ACP3CYP1A2MTNR1AKMT2ATSHR | |
| SCHEMBL30307853 | 0.81 | TDP1 (0.67) | TDP1FFAR1AKR1B1CYP1A2MTNR1A | |
| SCHEMBL1218835 | 0.81 | TDP1 (0.67) | TDP1FFAR1AKR1B1CYP1A2MTNR1A | |
| SCHEMBL27811913 | 0.79 | ACP3 (0.68) | TDP1ACP3CYP1A2MTNR1AGPR84 | |
| Hydrochloric Acid SCHEMBL11319694 | 0.79 | TDP1 (0.65) | TDP1FFAR1AKR1B1CYP1A2MTNR1A | |
| SCHEMBL23881887 | 0.79 | TDP1 (0.46) | TDP1ACP3FFAR1AKR1B1CYP1A2 | |
| SCHEMBL2314388 | 0.78 | MEN1 (0.66) | TDP1FFAR1AKR1B1CYP1A2MTNR1A | |
| SCHEMBL5054516 | 0.77 | ACP3 (0.46) | TDP1ACP3CYP1A2MTNR1ACMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146524-A1 | Selective inhibitors of neurotensin degrading enzymes | SOLVAY PHARMACEUTICALS B.V. | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146524-A1 | Selective inhibitors of neurotensin degrading enzymes | COMT, NTSR1, CMA1 | TDP1 506/4885ACP3 1607/4885FFAR1 3075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.