Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.40 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4989844 | 0.87 | TDP1 (0.53) | ACP3TDP1TSHRCYP1A2FFAR1 | |
| SCHEMBL6037860 | 0.84 | ACP3 (0.50) | ACP3TDP1 | |
| SCHEMBL4988577 | 0.81 | TSHR (0.57) | ACP3TSHRCYP1A2KMT2AKDM4E | |
| SCHEMBL5060011 | 0.80 | GRM3 (0.54) | ACP3 | |
| SCHEMBL340395 | 0.80 | TSHR (0.62) | TSHRCYP1A2FFAR1ALDH1A1 | |
| SCHEMBL31587574 | 0.77 | ACP3 (1.00) | ACP3TDP1CYP1A2CTNNB1MTNR1A | |
| SCHEMBL233333 | 0.77 | ACP3 (1.00) | ACP3TDP1CYP1A2CTNNB1MTNR1A | |
| SCHEMBL3942725 | 0.76 | TDP1 (0.46) | ACP3TDP1CYP1A2FFAR1AKR1B1 | |
| SCHEMBL30567524 | 0.76 | TDP1 (0.46) | ACP3TDP1CYP1A2FFAR1AKR1B1 | |
| SCHEMBL23881752 | 0.76 | ACP3 (0.54) | ACP3TDP1CYP1A2FFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146524-A1 | Selective inhibitors of neurotensin degrading enzymes | SOLVAY PHARMACEUTICALS B.V. | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146524-A1 | Selective inhibitors of neurotensin degrading enzymes | COMT, NTSR1, CMA1 | ACP3 1607/4885TDP1 506/4885TSHR 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.