Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 9/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.35 |
| ▸ | PIK3R5 | Q8WYR1 | 1/20 | 0.35 |
| ▸ | PIK3R3 | Q92569 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784079 | 0.91 | PIK3CD (0.37) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R2 | |
| SCHEMBL5782323 | 0.88 | HRH3 (0.41) | OXTRAVPR1AKDM1ASMN1; SMN2REN | |
| SCHEMBL4988825 | 0.88 | HPGD (0.36) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R2 | |
| SCHEMBL5785686 | 0.87 | HPGD (0.38) | OXTRAVPR1ASMN1; SMN2RENGABRA5 | |
| SCHEMBL4988846 | 0.87 | ALDH1A1 (0.39) | OXTRAVPR1APIK3CDPIK3CAPIK3CB | |
| SCHEMBL14186820 | 0.82 | OXTR (0.41) | OXTRAVPR1ASMN1; SMN2GABRA5P2RX7 | |
| SCHEMBL4984447 | 0.81 | OXTR (0.41) | OXTRAVPR1ASMN1; SMN2GABRA5P2RX7 | |
| SCHEMBL4984451 | 0.80 | OXTR (0.40) | OXTRAVPR1ASMN1; SMN2GABRA5P2RX7 | |
| SCHEMBL4987250 | 0.79 | BRD4 (0.42) | KDM1APIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5785285 | 0.79 | KMT2A (0.43) | OXTRAVPR1ASMN1; SMN2GABRA5P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-05-29 | — | — | US | disclosed |
| EP-1803719-A1 | 1,5-DIHETEROCYCLE-1H-TRIAZOLE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125409-A1 | 1,5-Diheterocycle-1H-Triazole Derivative | PTGS1, PTGER1, TBXA2R | OXTR 2187/4885AVPR1A 548/4885KDM1A 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.