Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 9/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | BRD2 | P25440 | 1/20 | 0.51 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.51 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509193 | 0.84 | ALDH1A1 (0.62) | LMNAMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL1137531 | 0.83 | BRD4 (0.70) | LMNAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4994006 | 0.82 | HDAC3 (0.56) | PTGER3LMNAMAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11454825 | 0.81 | BRD4 (0.68) | LMNAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4986527 | 0.81 | BRD4 (0.47) | LMNAMAPTTHRBKDM4EALDH1A1 | |
| SCHEMBL4993830 | 0.81 | BRD4 (0.57) | LMNAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1770083 | 0.80 | EGLN1 (0.62) | PTGER3LMNAMAP3K14KDM4EALDH1A1 | |
| SCHEMBL31466359 | 0.80 | LMNA (0.77) | PTGER3LMNAMAP3K14KDM4EALDH1A1 | |
| SCHEMBL4553258 | 0.80 | MCL1 (0.53) | LMNAMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4984192 | 0.79 | RXFP1 (0.60) | LMNAMAPTTHRBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | PTGER3 80/4885LMNA 809/4885MAP3K14 1180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.