Diphenylsulfane

Diphenylsulfane

SCHEMBL4990263

O=S(=O)(Oc1ccc(F)cc1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.42
PIK3CA P42336 1/20 0.42
PIK3CB P42338 1/20 0.42
CA1 P00915 11/20 0.39
CA2 P00918 11/20 0.39
STS P08842 1/20 0.38
JAK2 O60674 1/20 0.34
JAK3 P52333 1/20 0.34
PTK2 Q05397 1/20 0.34
FFAR1 O14842 2/20 0.33
CA12 O43570 2/20 0.33
FFAR4 Q5NUL3 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33
PTGS2 P35354 1/20 0.32
NR3C1 P04150 1/20 0.32
GLA P06280 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylsulfane SCHEMBL1772327 0.94 PIK3CD (0.45) PIK3CDPIK3CAPIK3CBCA1CA2
Diphenylsulfane SCHEMBL6501320 0.93 STS (0.45) PIK3CDPIK3CAPIK3CBCA1CA2
SCHEMBL2572784 0.93 STS (0.45) PIK3CDPIK3CAPIK3CBCA1CA2
Diphenylsulfane SCHEMBL2902245 0.88 PIK3CD (0.41) PIK3CDPIK3CAPIK3CBCA1CA2
Diphenylsulfane SCHEMBL4999052 0.88 PIK3CD (0.41) PIK3CDPIK3CAPIK3CBCA1CA2
Diphenylsulfane SCHEMBL18863901 0.88 PIK3CD (0.41) PIK3CDPIK3CAPIK3CBCA1CA2
SCHEMBL31299570 0.87 CA2 (0.47) PIK3CDPIK3CAPIK3CBCA1CA2
Diphenylsulfane SCHEMBL5648428 0.86 PIK3CD (0.41) PIK3CDPIK3CAPIK3CBCA1CA2
Diphenylsulfane SCHEMBL2896196 0.85 PIK3CD (0.40) PIK3CDPIK3CAPIK3CBCA1CA2
Diphenylsulfane SCHEMBL5650013 0.85 JAK2 (0.47) PIK3CDPIK3CAPIK3CBCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7371503-B2 Sulfonium salt compound, photoacid generator, and positive-tone radiation-sensitive resin composition JSR CORPORATION (JP) 2008-05-13 US disclosed
US-20060141383-A1 Sulfonium salts, radiation- sensitive acid generators, and positive radiator-sensitive resin compositions JSR CORPORATION (JP) 2006-06-29 US disclosed