Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPOR | P19235 | 4/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.56 |
| ▸ | TLR4 | O00206 | 1/20 | 0.54 |
| ▸ | TLR2 | O60603 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990855 | 1.00 | EPOR (0.62) | EPORALOX5PTGS1PTGS2ALOX5AP | |
| SCHEMBL9492638 | 0.83 | EPOR (0.58) | EPORALOX5PTGS1PTGS2ALOX5AP | |
| SCHEMBL9359231 | 0.83 | EPOR (0.62) | EPORALOX5PTGS1PTGS2ALOX5AP | |
| SCHEMBL30721682 | 0.83 | EPOR (0.62) | EPORALOX5PTGS1PTGS2ALOX5AP | |
| SCHEMBL9130834 | 0.83 | ALOX5 (0.59) | EPORALOX5PTGS1PTGS2ALOX5AP | |
| SCHEMBL11157827 | 0.83 | EPOR (0.62) | EPORALOX5PTGS1PTGS2ALOX5AP | |
| SCHEMBL9492646 | 0.83 | EPOR (0.58) | EPORALOX5PTGS1PTGS2ALOX5AP | |
| SCHEMBL9130816 | 0.83 | ALOX5 (0.59) | EPORALOX5PTGS1PTGS2ALOX5AP | |
| SCHEMBL27900292 | 0.81 | TLR4 (0.64) | EPORALOX5PTGS1PTGS2ALOX5AP | |
| SCHEMBL9487834 | 0.81 | RELA (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279531-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF INSECTICIDALLY ACTIVE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-10 | — | — | EP | claimed |
| EP-0279531-A2 | Process and intermediates for the preparation of insecticidally active compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-24 | — | — | EP | claimed |
| US-7384979-B2 | Substituted amino acids as erythropoietin mimetics | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2008-06-10 | — | — | US | disclosed |
| EP-1073623-B1 | SUBSTITUTED AMINO ACIDS AS ERYTHROPOIETIN MIMETICS | ORTHO MCNEIL PHARM INC (US) | 2007-04-11 | — | — | EP | disclosed |
| US-7153869-B2 | Substituted amino acids as erythropoietin mimetics | CONNOLLY PETER J | 2006-12-26 | — | — | US | disclosed |
| US-20060247274-A1 | Substituted amino acids as erythropoietin mimetics | CONNOLLY PETER J | 2006-11-02 | — | — | US | disclosed |
| US-20040248815-A1 | Substituted amino acids as erythropoietin mimetics | ORTHO MCNEIL PHARMACEUTICAL, INC. | 2004-12-09 | — | — | US | disclosed |
| EP-1073623-A4 | SUBSTITUTED AMINO ACIDS AS ERYTHROPOIETIN MIMETICS | ORTHO MCNEIL PHARM INC (US) | 2004-08-18 | — | — | EP | disclosed |
| US-6750369-B2 | USEFUL IN TREATMENT OF DISEASES OR CONDITIONS ASSOCIATED WITH ERYTHROPOIETIN RECEPTOR | ORTHO MCNEIL PHARMACEUTICAL, INC. | 2004-06-15 | — | — | US | disclosed |
| US-20020016350-A1 | Substituted amino acids as erythropoietin mimetics | CONNOLLY PETER J (US) | 2002-02-07 | — | — | US | disclosed |
| US-6310078-B1 | MODULATING ERYTHROPOIETIN RECEPTOR, TREATING DISEASE OR CONDITION MEDIATED BY SAID RECEPTOR | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2001-10-30 | — | — | US | disclosed |
| EP-1073623-A1 | SUBSTITUTED AMINO ACIDS AS ERYTHROPOIETIN MIMETICS | Ortho-Mcneil Pharmaceutical, Inc. (US) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999054279-A1 | SUBSTITUTED AMINO ACIDS AS ERYTHROPOIETIN MIMETICS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 1999-10-28 | — | — | WO | disclosed |
| EP-0279531-B1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF INSECTICIDALLY ACTIVE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-10 | — | — | EP | disclosed |
| US-5081273-A | PROCESS FOR THE PREPARATION OF INSECTICIDALLY ACTIVE DIPHENYL ETHER COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-14 | — | — | US | disclosed |
| US-4942264-A | WITTIG REACTION FOLLOWED BY REDUCTION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-07-17 | — | — | US | disclosed |
| EP-0279531-A2 | Process and intermediates for the preparation of insecticidally active compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247274-A1 | Substituted amino acids as erythropoietin mimetics | EPOR, EDNRA, EDNRB | EPOR 1/4885ALOX5 3531/4885PTGS1 1241/4885 |
| US-20020016350-A1 | Substituted amino acids as erythropoietin mimetics | EPOR, EDNRA, FLT1 | EPOR 1/4885ALOX5 3840/4885PTGS1 976/4885 |
| US-20040248815-A1 | Substituted amino acids as erythropoietin mimetics | EPOR, EDNRA, FLT1 | EPOR 1/4885ALOX5 3840/4885PTGS1 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.