SCHEMBL4990933

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4990020	0.90	TAAR1 (0.47)	HTR2AHTR2BHTR2CPPARAEPHX1
	SCHEMBL4989699	0.89	PPARA (0.51)	HTR2AHTR2BHTR2CPPARAEPHX1
	SCHEMBL4993135	0.86	HTR2A (0.55)	HTR2AHTR2BHTR2CPPARAEPHX1
	SCHEMBL4993849	0.85	PPARA (0.55)	PPARAPPARGEPHX2
	SCHEMBL1816528	0.84	HTR2A (0.56)	HTR2AHTR2BHTR2CPPARAEPHX1
	SCHEMBL4986177	0.83	TAAR1 (0.47)	HTR2AHTR2BHTR2CPPARAEPHX1
	SCHEMBL4989989	0.82	CYP1A2 (0.51)	PPARGCYP1A2
	SCHEMBL4993636	0.82	PNMT (0.46)	PPARAPPARGTAAR1
	SCHEMBL5095202	0.81	PPARA (0.64)	HTR2AHTR2BHTR2CPPARAADRA2C
	SCHEMBL4992250	0.81	TAAR1 (0.45)	HTR2AHTR2BHTR2CPPARAEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.