SCHEMBL499273

SCHEMBL499273

C=CC(=O)OC(CCCCC)N(C)C

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
HPGD P15428 1/20 0.44
THRB P10828 2/20 0.39
THRA P10827 1/20 0.35
ZDHHC20 Q5W0Z9 2/20 0.35
ZDHHC2 Q9UIJ5 2/20 0.35
GPR84 Q9NQS5 3/20 0.34
CA1 P00915 2/20 0.34
FFAR1 O14842 1/20 0.34
ZDHHC7 Q9NXF8 1/20 0.34
FAAH O00519 2/20 0.33
MAPT P10636 1/20 0.33
ABCB1 P08183 1/20 0.33
LCK P06239 1/20 0.33
PPARD Q03181 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11673372 0.98 TSHR (0.43) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL499747 0.98 TSHR (0.43) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL499540 0.98 TSHR (0.43) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL5247453 0.95 TSHR (0.49) TSHRHPGDTHRBTHRAZDHHC20
SCHEMBL151180 0.88 TSHR (0.40) TSHRHPGDTHRB
SCHEMBL28373823 0.87 TSHR (0.42) TSHRHPGDTHRBTHRAZDHHC20
Bromide SCHEMBL1303185 0.86 TSHR (0.39) TSHRHPGDTHRB
SCHEMBL543768 0.86 ATM (0.41) TSHRZDHHC20ZDHHC2GPR84CA1
Hydrochloric Acid SCHEMBL1303097 0.86 TSHR (0.39) TSHRHPGDTHRB
SCHEMBL544701 0.86 ATM (0.41) TSHRZDHHC20ZDHHC2GPR84CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5321110-A Thickeners for shampoo, hair conditioners ISP INVESTMENTS INC. (US) 1994-06-14 US claimed
EP-0106193-A2 Liquid skin cleanser composition UNION CARBIDE CORPORATION (US) 1984-04-25 EP claimed
US-3954960-A Hair and similar cosmetic preparations containing a quaternized copolymer of vinyl pyrrolidone GAF CORPORATION (US) 1976-05-04 US claimed
CN-120158166-A Adhesive slurry and preparation method thereof, coating diaphragm and preparation method thereof 浙江盈博莱新能源有限公司 2025-06-17 CN disclosed
US-12096767-B2 Residual disinfectant composition KIMBERLY-CLARK WORLDWIDE, INC. (US) 2024-09-24 US disclosed
US-20230277704-A1 Disinfectant Composition with Rapid Antiviral Efficacy KIMBERLY-CLARK WORLDWIDE, INC. 2023-09-07 US disclosed
EP-3328373-B1 DISINFECTANT COMPOSITION WITH RAPID ANTIVIRAL EFFICACY KIMBERLY CLARK CO (US) 2023-06-07 EP disclosed
EP-3569682-B1 LIQUID HARD SURFACE CLEANING COMPOSITIONS HAVING IMPROVED VISCOSITY PROCTER & GAMBLE (US) 2022-12-07 EP disclosed
WO-2022162221-A1 DETERGENT COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2022-08-04 WO disclosed
US-10995302-B2 Liquid acidic hard surface cleaning compositions having improved viscosity THE PROCTER & GAMBLE COMPANY (US) 2021-05-04 US disclosed
US-20210092949-A1 Residual Disinfectant Composition KIMBERLY-CLARK WORLDWIDE, INC. 2021-04-01 US disclosed
US-4362528-A OXIDATION COLOR DYE,CATIONIC POLYMER TO IMPROVE FEEL,SHAMPOO WITH ANIONIC DETERGENT SOCIETE ANONYME DITE: L'OREAL (FR) 1982-12-07 US disclosed
EP-0047009-A1 Hydrophilic interpolymers of acrylic acid and an olefin or a styrene The B.F. GOODRICH Company (US) 1982-03-10 EP disclosed
US-4314807-A CATIONIC POLYMER, ANIONIC SURFACTANT SHAMPOO L'OREAL (FR) 1982-02-09 US disclosed
EP-0042502-A1 Cationic polymers and their use in electrodeposition PPG INDUSTRIES, INC. (US) 1981-12-30 EP disclosed
US-4294741-A QUATERNARY AMMONIUM POLYMER FORMED FROM A POLYEPOXIDE AND AN UNSATURATED TERTIARY AMINE PPG INDUSTRIES, INC. (US) 1981-10-13 US disclosed
US-4020192-A AMINO ALKYL AMIDE ACRYLIC POLYMER FUJI XEROX CO., LTD. (JA) 1977-04-26 US disclosed
US-3980769-A ANIONIC AND AMPHOTERIC SURFACTANTS L'OREAL (FR) 1976-09-14 US disclosed
US-3958581-A Cosmetic composition containing a cationic polymer and divalent metal salt for strengthening the hair L'OREAL (FR) 1976-05-25 US disclosed
US-3954960-A Hair and similar cosmetic preparations containing a quaternized copolymer of vinyl pyrrolidone GAF CORPORATION (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210092949-A1 Residual Disinfectant Composition QARS1, EIF2AK2, POLL TSHR 2755/4885HPGD 4715/4885THRB 4598/4885
US-12096767-B2 Residual disinfectant composition QARS1, EIF2AK2, POLL TSHR 2755/4885HPGD 4715/4885THRB 4598/4885
US-20230277704-A1 Disinfectant Composition with Rapid Antiviral Efficacy EIF2AK2, APOBEC3A, APOBEC3C TSHR 2150/4885HPGD 2149/4885THRB 4223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.