SCHEMBL499747

SCHEMBL499747

C=CC(=O)OC(CCCCCCCCCCCCCCCCC)N(C)C

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.43
HPGD P15428 1/20 0.43
THRB P10828 2/20 0.38
ZDHHC20 Q5W0Z9 2/20 0.38
ZDHHC2 Q9UIJ5 2/20 0.38
THRA P10827 1/20 0.38
GPR84 Q9NQS5 5/20 0.37
FFAR1 O14842 1/20 0.37
ZDHHC7 Q9NXF8 1/20 0.37
MAPT P10636 1/20 0.36
LCK P06239 1/20 0.36
PPARD Q03181 1/20 0.36
FAAH O00519 1/20 0.36
ABCB1 P08183 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL499540 1.00 TSHR (0.43) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL11673372 1.00 TSHR (0.43) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL499273 0.98 TSHR (0.44) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL5247453 0.93 TSHR (0.49) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL151180 0.86 TSHR (0.40) TSHRHPGDTHRBALDH1A1CYP3A4
SCHEMBL28373823 0.86 TSHR (0.42) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL499683 0.86 TSHR (0.42) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL19856505 0.86 TSHR (0.34) TSHRHPGDALDH1A1CYP3A4
SCHEMBL500591 0.86 TSHR (0.42) TSHRHPGDTHRBZDHHC20ZDHHC2
SCHEMBL499596 0.86 TSHR (0.42) TSHRHPGDTHRBZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5321110-A Thickeners for shampoo, hair conditioners ISP INVESTMENTS INC. (US) 1994-06-14 US claimed
US-3954960-A Hair and similar cosmetic preparations containing a quaternized copolymer of vinyl pyrrolidone GAF CORPORATION (US) 1976-05-04 US claimed
US-12096767-B2 Residual disinfectant composition KIMBERLY-CLARK WORLDWIDE, INC. (US) 2024-09-24 US disclosed
US-20230277704-A1 Disinfectant Composition with Rapid Antiviral Efficacy KIMBERLY-CLARK WORLDWIDE, INC. 2023-09-07 US disclosed
EP-3328373-B1 DISINFECTANT COMPOSITION WITH RAPID ANTIVIRAL EFFICACY KIMBERLY CLARK CO (US) 2023-06-07 EP disclosed
EP-3569682-B1 LIQUID HARD SURFACE CLEANING COMPOSITIONS HAVING IMPROVED VISCOSITY PROCTER & GAMBLE (US) 2022-12-07 EP disclosed
WO-2022162221-A1 DETERGENT COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2022-08-04 WO disclosed
US-10995302-B2 Liquid acidic hard surface cleaning compositions having improved viscosity THE PROCTER & GAMBLE COMPANY (US) 2021-05-04 US disclosed
US-20210092949-A1 Residual Disinfectant Composition KIMBERLY-CLARK WORLDWIDE, INC. 2021-04-01 US disclosed
US-10920180-B2 Liquid acidic hard surface cleaning compositions providing improved maintenance of surface shine, and prevention of water marks and splash marks THE PROCTER & GAMBLE COMPANY (US) 2021-02-16 US disclosed
US-10874100-B2 Residual disinfectant composition KIMBERLY-CLARK WORLDWIDE, INC. (US) 2020-12-29 US disclosed
US-20050159321-A1 Disinfecting compositions containing a polymer complex of an organic acid RECKITT BENCKISER INC MORRIS CORPORATE CENTER IV (US) 2005-07-21 US disclosed
EP-1531671-A1 DISINFECTING COMPOSITIONS CONTAINING A POLYMER COMPLEX OF AN ORGANIC ACID Reckitt Benckiser Inc. (US) 2005-05-25 EP disclosed
EP-1442110-A1 HARD SURFACE CLEANING AND DISINFECTING COMPOSITIONS Reckitt Benckiser Inc. (US) 2004-08-04 EP disclosed
WO-2004016087-A1 DISINFECTING COMPOSITIONS CONTAINING A POLYMER COMPLEX OF AN ORGANIC ACID RECKITT BENCKISER INC. (US) 2004-02-26 WO disclosed
WO-2003038025-A1 HARD SURFACE CLEANING AND DISINFECTING COMPOSITIONS RECKITT BENCKISER INC (US) 2003-05-08 WO disclosed
US-5321110-A Thickeners for shampoo, hair conditioners ISP INVESTMENTS INC. (US) 1994-06-14 US disclosed
US-5045617-A Zwitterion terpolymers of a vinyl lactam, an amino alkyl acrylamide or acrylate, and a polymerizable carboxylic acid ISP INVESTMENTS INC. (US) 1991-09-03 US disclosed
US-3980769-A ANIONIC AND AMPHOTERIC SURFACTANTS L'OREAL (FR) 1976-09-14 US disclosed
US-3954960-A Hair and similar cosmetic preparations containing a quaternized copolymer of vinyl pyrrolidone GAF CORPORATION (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210092949-A1 Residual Disinfectant Composition QARS1, EIF2AK2, POLL TSHR 2755/4885HPGD 4715/4885THRB 4598/4885
US-12096767-B2 Residual disinfectant composition QARS1, EIF2AK2, POLL TSHR 2755/4885HPGD 4715/4885THRB 4598/4885
US-10874100-B2 Residual disinfectant composition QARS1, EIF2AK2, POLL TSHR 2755/4885HPGD 4715/4885THRB 4598/4885
US-20230277704-A1 Disinfectant Composition with Rapid Antiviral Efficacy EIF2AK2, APOBEC3A, APOBEC3C TSHR 2150/4885HPGD 2149/4885THRB 4223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.