Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL544701 | 1.00 | ATM (0.41) | ATMHCAR2GPR84CA1FFAR1 | |
| SCHEMBL29134002 | 0.87 | HCAR2 (0.44) | ATMHCAR2CA1TSHRLMNA | |
| SCHEMBL499273 | 0.86 | TSHR (0.44) | GPR84CA1FFAR1ZDHHC7TSHR | |
| SCHEMBL499540 | 0.85 | TSHR (0.43) | GPR84FFAR1ZDHHC7TSHRLMNA | |
| SCHEMBL499747 | 0.85 | TSHR (0.43) | GPR84FFAR1ZDHHC7TSHRLMNA | |
| SCHEMBL11673372 | 0.85 | TSHR (0.43) | GPR84FFAR1ZDHHC7TSHRLMNA | |
| SCHEMBL7707564 | 0.81 | FAAH (0.40) | GPR84CA1FFAR1ZDHHC7LMNA | |
| SCHEMBL5247453 | 0.81 | TSHR (0.49) | ATMCA1TSHRZDHHC20ZDHHC2 | |
| SCHEMBL7710315 | 0.80 | FAAH (0.42) | GPR84FFAR1ZDHHC7LMNAMAPT | |
| SCHEMBL9128093 | 0.80 | FAAH (0.42) | GPR84FFAR1ZDHHC7LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110625-B2 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2012-02-07 | — | — | US | disclosed |
| EP-2223958-B1 | Rubber composition | BRIDGESTONE CORP (JP) | 2011-12-28 | — | — | EP | disclosed |
| US-20100298488-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2010-11-25 | — | — | US | disclosed |
| US-7799856-B2 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| EP-2226354-A1 | Rubber composition | Bridgestone Corporation (JP) | 2010-09-08 | — | — | EP | disclosed |
| EP-2223958-A1 | Rubber composition | Bridgestone Corporation (JP) | 2010-09-01 | — | — | EP | disclosed |
| EP-1435375-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2004-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298488-A1 | RUBBER COMPOSITION | RAD50, RAD54L, VCL | ATM 197/4885HCAR2 2134/4885GPR84 2059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.