Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4999591 | 1.00 | MTNR1A (0.55) | MTNR1AMTNR1BSIRT2FFAR1PLA2G4B | |
| SCHEMBL4982213 | 1.00 | MTNR1A (0.55) | MTNR1AMTNR1BSIRT2FFAR1PLA2G4B | |
| SCHEMBL3982936 | 1.00 | MTNR1A (0.55) | MTNR1AMTNR1BSIRT2FFAR1PLA2G4B | |
| SCHEMBL4980983 | 0.99 | MTNR1A (0.56) | MTNR1AMTNR1BSIRT2FFAR1PLA2G4B | |
| SCHEMBL4983098 | 0.95 | SIRT2 (0.52) | MTNR1AMTNR1BSIRT2FFAR1LPAR1 | |
| SCHEMBL3982083 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL3978617 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL3975780 | 0.91 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL3973759 | 0.90 | MTNR1A (0.51) | MTNR1AMTNR1B | |
| SCHEMBL3978236 | 0.89 | ACHE (0.46) | MTNR1AMTNR1BPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113975-A1 | THIOUREA COMPOUNDS | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113975-A1 | THIOUREA COMPOUNDS | TPMT, HAVCR2, EIF2AK2 | MTNR1A 4383/4885MTNR1B 3688/4885SIRT2 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.