Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 1.00 |
| ▸ | PAX8 | Q06710 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | SLCO4C1 | Q6ZQN7 | 1/20 | 1.00 |
| ▸ | ATP1A1 | P05023 | 9/20 | 0.74 |
| ▸ | ATP1B1 | P05026 | 9/20 | 0.74 |
| ▸ | ATP1B2 | P14415 | 9/20 | 0.74 |
| ▸ | ATP1A2 | P50993 | 9/20 | 0.74 |
| ▸ | ATP1B3 | P54709 | 9/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.74 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.74 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Digoxigenin SCHEMBL13337910 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL8816469 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL21105 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL24012132 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL13362000 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL23827178 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL12841138 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL11077489 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL8816474 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL29477343 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| US-11573224-B2 | Methods of detection using X-ray fluorescence | ICAGEN, LLC (US) | 2023-02-07 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-10877035-B2 | Advanced drug development and manufacturing | ICAGEN, LLC (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200278346-A1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ADJACENT ACQUISITION CO., LLC | 2020-09-03 | — | — | US | disclosed |
| WO-2020020728-A1 | 17BETA-HETEROCYCLYL-DIGITALIS LIKE COMPOUNDS FOR THE TREATMENT OF HEART FAILURE | UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA (IT) | 2020-01-30 | — | — | WO | disclosed |
| EP-3599243-A1 | 17BETA-HETEROCYCLYL-DIGITALIS LIKE COMPOUNDS FOR THE TREATMENT OF HEART FAILURE | CVIE Therapeutics Limited (TW) | 2020-01-29 | — | — | EP | disclosed |
| WO-2018122043-A1 | NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2018-07-05 | — | — | WO | disclosed |
| US-20150309021-A1 | Advanced Drug Development and Manufacturing | LOS ALAMOS NATIONAL SECURITY, LLC | 2015-10-29 | — | — | US | disclosed |
| EP-2511844-B1 | X-ray microscope | XRPRO SCIENCES INC (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2511844-A2 | Advanced drug development and manufacturing | Los Alamos National Security, LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| EP-2084519-B1 | X-RAY FLUORESCENCE ANALYSIS METHOD | LOS ALAMOS NAT SECURITY LLC (US) | 2012-08-01 | — | — | EP | disclosed |
| EP-0710667-B1 | Modified oligonucleotides, their preparation and their use | ROCHE DIAGNOSTICS GMBH (DE) | 2011-12-14 | — | — | EP | disclosed |
| US-7635571-B2 | photosenstizer generates singlet oxygen which oxidatively cleaves the linker to form a product which can be detected in a sandwich detection assay; kits | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-7635571-B2 | photosenstizer generates singlet oxygen which oxidatively cleaves the linker to form a product which can be detected in a sandwich detection assay; kits | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-20080220441-A1 | Advanced drug development and manufacturing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-11 | — | — | US | disclosed |