Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 1.00 |
| ▸ | PAX8 | Q06710 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | NPC1 | O15118 | 3/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | SLCO4C1 | Q6ZQN7 | 1/20 | 1.00 |
| ▸ | ATP1A1 | P05023 | 9/20 | 0.74 |
| ▸ | ATP1B1 | P05026 | 9/20 | 0.74 |
| ▸ | ATP1B2 | P14415 | 9/20 | 0.74 |
| ▸ | ATP1A2 | P50993 | 9/20 | 0.74 |
| ▸ | ATP1B3 | P54709 | 9/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.74 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.74 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Digoxigenin SCHEMBL13337910 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL4994463 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL21105 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL24012132 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL13362000 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL23827178 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL12841138 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL11077489 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL8816474 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A | |
| Digoxigenin SCHEMBL29477343 | 1.00 | TP53 (1.00) | TP53PAX8LMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647133-A4 | COMPOSITIONS AND METHODS FOR ENHANCED DRUG DELIVERY. | AFFYMAX TECH NV (AN) | 1997-10-29 | — | — | EP | disclosed |
| US-5607691-A | IONTOPHORESIS | AFFYMAX TECHNOLOGIES N.V. (GB) | 1997-03-04 | — | — | US | disclosed |
| EP-0647133-A1 | COMPOSITIONS AND METHODS FOR ENHANCED DRUG DELIVERY | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-04-12 | — | — | EP | disclosed |
| WO-1993025197-A1 | COMPOSITIONS AND METHODS FOR ENHANCED DRUG DELIVERY | AFFYMAX TECHNOLOGIES N.V. (AN) | 1993-12-23 | — | — | WO | disclosed |