Digoxigenin

Digoxigenin

SCHEMBL29477343

C[C@]12CC[C@H](O)C[C@@H]1CC[C@@H]1[C@@H]2C[C@@H](O)[C@]2(C)[C@@H](C3=CC(=O)OC3)CC[C@]12O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TP53 P04637 6/20 1.00
▸ PAX8 Q06710 4/20 1.00
▸ LMNA P02545 4/20 1.00
▸ SMN1; SMN2 Q16637 4/20 1.00
▸ RAB9A P51151 4/20 1.00
▸ HIF1A Q16665 3/20 1.00
▸ NPC1 O15118 3/20 1.00
▸ CYP2C19 P33261 2/20 1.00
▸ HSD17B10 Q99714 1/20 1.00
▸ SLCO4C1 Q6ZQN7 1/20 1.00
▸ ATP1A1 P05023 9/20 0.74
▸ ATP1B1 P05026 9/20 0.74
▸ ATP1B2 P14415 9/20 0.74
▸ ATP1A2 P50993 9/20 0.74
▸ ATP1B3 P54709 9/20 0.74
▸ TSHR P16473 2/20 0.74
▸ ATP1A3 P13637 2/20 0.74
▸ FXYD2 P54710 2/20 0.74
▸ ATP1A4 Q13733 2/20 0.74
▸ CYP3A4 P08684 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Digoxigenin SCHEMBL13337910 1.00 TP53 (1.00) TP53PAX8LMNASMN1; SMN2RAB9A
Digoxigenin SCHEMBL8816469 1.00 TP53 (1.00) TP53PAX8LMNASMN1; SMN2RAB9A
Digoxigenin SCHEMBL4994463 1.00 TP53 (1.00) TP53PAX8LMNASMN1; SMN2RAB9A
Digoxigenin SCHEMBL21105 1.00 TP53 (1.00) TP53PAX8LMNASMN1; SMN2RAB9A
Digoxigenin SCHEMBL24012132 1.00 TP53 (1.00) TP53PAX8LMNASMN1; SMN2RAB9A
Digoxigenin SCHEMBL13362000 1.00 TP53 (1.00) TP53PAX8LMNASMN1; SMN2RAB9A
Digoxigenin SCHEMBL23827178 1.00 TP53 (1.00) TP53PAX8LMNASMN1; SMN2RAB9A
Digoxigenin SCHEMBL12841138 1.00 TP53 (1.00) TP53PAX8LMNASMN1; SMN2RAB9A
Digoxigenin SCHEMBL11077489 1.00 TP53 (1.00) TP53PAX8LMNASMN1; SMN2RAB9A
Digoxigenin SCHEMBL8816474 1.00 TP53 (1.00) TP53PAX8LMNASMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139300-A1 NUCLEIC ACID CONCATEMERS AND METHODS FOR STABILIZING AND/OR COMPACTING THE SAME 10X GENOMICS INC (US) 2026-05-21 — — US disclosed
US-20260139301-A1 CATALYTIC DE-CROSSLINKING OF SAMPLES FOR IN SITU ANALYSIS 10X GENOMICS INC (US) 2026-05-21 — — US disclosed
US-20260139302-A1 METHODS AND COMPOSITIONS FOR IN SITU ANALYSIS OF V(D)J SEQUENCES 10X GENOMICS INC (US) 2026-05-21 — — US disclosed
US-20260132444-A1 STABILIZATION AND/OR COMPACTION OF NUCLEIC ACID MOLECULES 10X GENOMICS, INC. (US) 2026-05-14 — — US disclosed
EP-4741513-A2 METHODS AND COMPOSITIONS FOR SYNCHRONIZING REACTIONS IN SITU 10X Genomics, Inc. (US) 2026-05-13 — — EP disclosed
US-20260125747-A1 PROBES COMPRISING A SPLIT BARCODE REGION AND METHODS OF USE 10X GENOMICS, INC. (US) 2026-05-07 — — US disclosed
EP-4573210-B1 METHOD FOR ANALYSING GENE EXPRESSION IN CELLS IN A PELLET 10X GENOMICS INC (US) 2026-05-06 — — EP disclosed
US-20260117287-A1 COMPOSITIONS AND METHODS FOR TARGETED MASKING OF AUTOFLUORESCENCE 10X GENOMICS INC (US) 2026-04-30 — — US disclosed
EP-4370896-B1 METHODS FOR PREPARING POLYMERIZED MATRIX WITH CONTROLLABLE THICKNESS 10X GENOMICS INC (US) 2026-04-29 — — EP disclosed
EP-4733410-A2 MULTIPLE READOUT SIGNALS FOR ANALYZING A SAMPLE 10X Genomics, Inc. (US) 2026-04-29 — — EP disclosed
US-20220282313-A1 CHEMICAL COMPOSITIONS AND USES THEREOF BRUKER SPATIAL BIOLOGY, INC. 2022-09-08 — — US disclosed
EP-4045887-A1 CLINICAL- AND INDUSTRIAL-SCALE INTACT-TISSUE SEQUENCING The Board of Trustees of the Leland Stanford Junior University (US) 2022-08-24 — — EP disclosed
WO-2022159474-A1 METHODS AND COMPOSITIONS FOR INTERNALLY CONTROLLED IN SITU ASSAYS 10X GENOMICS, INC. (US) 2022-07-28 — — WO disclosed
US-20220228200-A1 METHODS AND COMPOSITIONS FOR INTERNALLY CONTROLLED IN SITU ASSAYS 10X GENOMICS, INC. 2022-07-21 — — US disclosed
EP-4029952-A1 ENZYME- AND AMPLIFICATION-FREE SEQUENCING Nanostring Technologies, Inc (US) 2022-07-20 — — EP disclosed
US-20220213532-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING SAME BRUKER SPATIAL BIOLOGY, INC. 2022-07-07 — — US disclosed
US-20220162694-A1 DNA ARRAY COMPLETE GENOMICS, INC. 2022-05-26 — — US disclosed
US-20220136049-A1 SEQUENCE ANALYSIS USING META-STABLE NUCLEIC ACID MOLECULES 10X GENOMICS, INC. 2022-05-05 — — US disclosed
WO-2022060967-A1 CHEMICAL COMPOSITIONS AND METHODS OF USING THE SAME NANOSTRING TECHNOLOGIES, INC. (US) 2022-03-24 — — WO disclosed
US-11279969-B2 Chemical compositions and methods of using same NANOSTRING TECHNOLOGIES, INC. (US) 2022-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139300-A1 NUCLEIC ACID CONCATEMERS AND METHODS FOR STABILIZING AND/OR COMPACTING THE SAME INCENP, SLIRP, SMCHD1 TP53 247/4885PAX8 289/4885LMNA 126/4885
US-20260139301-A1 CATALYTIC DE-CROSSLINKING OF SAMPLES FOR IN SITU ANALYSIS RNGTT, NSUN2, POLL TP53 2961/4885PAX8 1640/4885LMNA 257/4885
US-20260117287-A1 COMPOSITIONS AND METHODS FOR TARGETED MASKING OF AUTOFLUORESCENCE FABP3, HNRNPM, B2M TP53 72/4885PAX8 1149/4885LMNA 211/4885
US-20260132444-A1 STABILIZATION AND/OR COMPACTION OF NUCLEIC ACID MOLECULES SLIRP, SMCHD1, INCENP TP53 519/4885PAX8 514/4885LMNA 40/4885
US-20260139302-A1 METHODS AND COMPOSITIONS FOR IN SITU ANALYSIS OF V(D)J SEQUENCES POLL, VSIR, BCR TP53 767/4885PAX8 496/4885LMNA 1216/4885
US-20260125747-A1 PROBES COMPRISING A SPLIT BARCODE REGION AND METHODS OF USE LIG1, LIG4, LIG3 TP53 649/4885PAX8 482/4885LMNA 451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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