⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317136 | 0.71 | — | — | |
| SCHEMBL866328 | 0.67 | — | — | |
| SCHEMBL3297413 | 0.67 | — | — | |
| SCHEMBL29057527 | 0.67 | — | — | |
| SCHEMBL4684 | 0.65 | — | — | |
| SCHEMBL1314613 | 0.65 | THRB (0.40) | — | |
| SCHEMBL128749 | 0.65 | — | — | |
| SCHEMBL8319541 | 0.65 | — | — | |
| SCHEMBL4994574 | 0.65 | — | — | |
| SCHEMBL4862 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022860-B2 | Tricyclic triazolobenzazepine derivatives, process for producing the same, and antiallergic agents | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-04-04 | — | — | US | claimed |
| EP-0650484-B1 | ENDOTHELIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2000-01-26 | — | — | EP | claimed |
| CN-117003875-A | Antibody or functional fragment thereof, polynucleotide, expression vector, host cell, sugar chain reconstruction antibody, pharmaceutical composition and application | 第一三共株式会社 | 2023-11-07 | — | — | CN | disclosed |
| CN-116999573-A | Antibody-drug conjugate, preparation method thereof, pharmaceutical composition and application thereof in preparation of drugs for treating tumors | 第一三共株式会社 | 2023-11-07 | — | — | CN | disclosed |
| CN-116999572-A | Antibody-drug conjugate, pharmaceutical composition and application thereof in preparation of drugs for treating tumors | 第一三共株式会社 | 2023-11-07 | — | — | CN | disclosed |
| CN-111164208-B | Antibody-pyrrolobenzodiazepine derivative conjugates | 第一三共株式会社 | 2023-08-04 | — | — | CN | disclosed |
| US-11628223-B2 | Antibody-drug conjugates comprising substituted benzo[e]pyrrolo[1,2-α][1,4]diazepines | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-04-18 | — | — | US | disclosed |
| US-20230084707-A1 | ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-03-16 | — | — | US | disclosed |
| US-11583590-B2 | Antibody-pyrrolobenzodiazepine derivative conjugate and method of use thereof for treating a tumor | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2023-02-21 | — | — | US | disclosed |
| US-20220395579-A1 | ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-12-15 | — | — | US | disclosed |
| US-20220125943-A1 | ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2022-04-28 | — | — | US | disclosed |
| WO-1997000849-A1 | NOVEL VINYL SULFIDE COMPOUNDS AND A PROCESS FOR THEIR PREPARATION | LUMIGEN, INC. (US) | 1997-01-09 | — | — | WO | disclosed |
| WO-1997000869-A1 | PROCESS FOR THE PREPARATION OF 1,2-DIOXETANE COMPOUNDS AND NOVEL SULFUR-SUBSTITUTED 1,2-DIOXETANE COMPOUNDS AS INTERMEDIATES | LUMIGEN, INC. (US) | 1997-01-09 | — | — | WO | disclosed |
| US-5543517-A | VIRICIDES | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-08-06 | — | — | US | disclosed |
| EP-0693496-A1 | Novel cephalosporins having a substituted benzyloxyimino radical in position 7, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1996-01-24 | — | — | EP | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |
| EP-0448412-B1 | A route to glycals in the allal and gulal series | UNIV YALE (US) | 1995-02-15 | — | — | EP | disclosed |
| US-5278301-A | Route to glycals in the allal and gulal series | YALE UNIVERSITY (US) | 1994-01-11 | — | — | US | disclosed |
| US-5104982-A | ROUTE TO GLYCALS IN THE ALLAL AND GULAL SERIES | YALE UNIVERSITY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0448412-A2 | A route to glycals in the allal and gulal series | YALE UNIVERSITY (US) | 1991-09-25 | — | — | EP | disclosed |