Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 7/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24130554 | 0.84 | NPC1 (0.57) | ITGAVNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL24130553 | 0.84 | NPC1 (0.57) | ITGAVNPC1RAB9ASMN1; SMN2GAA | |
| Benzene SCHEMBL8722272 | 0.77 | NPC1 (0.66) | ITGAVNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL7096522 | 0.77 | NPC1 (0.66) | ITGAVNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL8458584 | 0.76 | ITGB3 (0.75) | ITGAVITGB3ITGA2B | |
| SCHEMBL8458591 | 0.76 | ITGB3 (0.75) | ITGAVITGB3ITGA2B | |
| SCHEMBL7561649 | 0.76 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2GAAEPHX2 | |
| SCHEMBL24324149 | 0.75 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL1769064 | 0.75 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL10767093 | 0.75 | NPC1 (0.59) | ITGAVNPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511844-A2 | Advanced drug development and manufacturing | Los Alamos National Security, LLC (US) | 2012-10-17 | — | — | EP | disclosed |
| US-20080220441-A1 | Advanced drug development and manufacturing | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-11 | — | — | US | disclosed |