Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429492 | 0.90 | KDM5A (0.42) | KDM4EALDH1A1MYCLMNATSHR | |
| SCHEMBL4989816 | 0.85 | TTR (0.39) | KDM4EALDH1A1MYCLMNAHSD17B10 | |
| SCHEMBL4429455 | 0.85 | TSHR (0.44) | KDM4EALDH1A1MYCLMNATSHR | |
| SCHEMBL4429636 | 0.81 | SLC6A4 (0.47) | KDM4EALDH1A1LMNATSHRBRD4 | |
| SCHEMBL4993080 | 0.81 | ALDH1A1 (0.41) | KDM4EALDH1A1LMNATSHRHSD17B10 | |
| SCHEMBL4436595 | 0.78 | MYC (0.41) | KDM4EALDH1A1MYCLMNATSHR | |
| SCHEMBL12890135 | 0.78 | ALDH1A1 (0.47) | KDM4EALDH1A1MYCLMNATSHR | |
| SCHEMBL4986578 | 0.78 | KDM4E (0.43) | KDM4EALDH1A1CFTR | |
| SCHEMBL4429494 | 0.78 | KCNN4 (0.44) | KDM4EALDH1A1CFTRATMMAPT | |
| SCHEMBL20524639 | 0.77 | PTGS2 (0.51) | KDM4EALDH1A1MYCLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | KDM4E 2635/4885ALDH1A1 1639/4885MYC 3967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.