SCHEMBL4995783

SCHEMBL4995783

O=S(=O)(OS1(c2ccc3cc(C4CCCCC4)ccc3c2)CCCC1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.32
ABL1 P00519 2/20 0.32
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4997145 0.99 CA1 (0.31) BACE1ABL1CA1CA2
SCHEMBL4990177 0.84 ABL1 (0.34) ABL1CA1CA2
SCHEMBL5002205 0.84 CA1 (0.31) CA1CA2
SCHEMBL5002235 0.84 MAOA (0.33)
SCHEMBL4997241 0.83 CA1 (0.34) CA1CA2
SCHEMBL4991069 0.83 ABL1 (0.33) ABL1CA1CA2
SCHEMBL4999367 0.83 SLC6A4 (0.32)
SCHEMBL4996681 0.82 SLC6A4 (0.36)
SCHEMBL4996370 0.82 CA1 (0.32) CA1CA2
SCHEMBL5002116 0.82 AR (0.32) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7371503-B2 Sulfonium salt compound, photoacid generator, and positive-tone radiation-sensitive resin composition JSR CORPORATION (JP) 2008-05-13 US disclosed
US-20060141383-A1 Sulfonium salts, radiation- sensitive acid generators, and positive radiator-sensitive resin compositions JSR CORPORATION (JP) 2006-06-29 US disclosed
EP-1586570-A1 SULFONIUM SALTS, RADIATION-SENSITIVE ACID GENERATORS, AND POSITIVE RADIATION-SENSITIVE RESIN COMPOSITIONS JSR Corporation (JP) 2005-10-19 EP disclosed