Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 3/20 | 0.37 |
| ▸ | BCR | P11274 | 3/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 2/20 | 0.34 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4717244 | 0.94 | CDC7 (0.45) | CDC7ABL1BCRPIK3C3MAPKAPK2 | |
| SCHEMBL4717758 | 0.91 | CDC7 (0.62) | CDC7ABL1BCRPIK3C3MAPKAPK2 | |
| Trifluoroacetic Acid SCHEMBL4997521 | 0.87 | CDC7 (0.55) | CDC7ABL1BCRPIK3C3MAPKAPK2 | |
| Trifluoroacetic Acid SCHEMBL4790707 | 0.87 | CDC7 (0.52) | CDC7ABL1BCRPIK3C3MAPKAPK2 | |
| Trifluoroacetic Acid SCHEMBL4997167 | 0.86 | CDC7 (0.53) | CDC7PIK3C3PIM1PIM2ASIC1 | |
| Trifluoroacetic Acid SCHEMBL5000129 | 0.86 | CDC7 (0.53) | CDC7ABL1BCRPIK3C3MAPKAPK2 | |
| Trifluoroacetic Acid SCHEMBL4716136 | 0.85 | CDC7 (0.52) | CDC7PIK3C3MAPKAPK2PIM1PIM2 | |
| SCHEMBL4716236 | 0.85 | CDC7 (0.53) | CDC7ABL1BCRPIK3C3MAPKAPK2 | |
| Trifluoroacetic Acid SCHEMBL4715188 | 0.85 | CDC7 (0.52) | CDC7ABL1KDM5AKDM4CKDM5B | |
| Trifluoroacetic Acid SCHEMBL4713069 | 0.85 | CDC7 (0.51) | CDC7PIK3C3MAPKAPK2PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113971-A1 | PYRAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | HANAU CATHLEEN E | 2008-05-15 | — | — | US | disclosed |
| US-20040152739-A1 | Acyclic pyrazole compounds for the inhibition of mitogen activated protein kinase-activated protein kinase-2 | PHARMACIA CORPORATION | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113971-A1 | PYRAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | MKNK2, MAPKAPK2, MAP3K2 | CDC7 487/4885ABL1 563/4885BCR 3771/4885 |
| US-20040152739-A1 | Acyclic pyrazole compounds for the inhibition of mitogen activated protein kinase-activated protein kinase-2 | MAPKAPK2, MAP3K2, MAP4K2 | CDC7 331/4885ABL1 587/4885BCR 3139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.