Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.53 |
| ▸ | ASIC1 | P78348 | 4/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 9/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.32 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14188386 | 0.91 | CDC7 (0.63) | CDC7MAPKAPK2PIK3C3PIM1PIM2 | |
| Trifluoroacetic Acid SCHEMBL4997521 | 0.88 | CDC7 (0.55) | CDC7ASIC1MAPKAPK2PIK3C3PIM1 | |
| Trifluoroacetic Acid SCHEMBL4716136 | 0.86 | CDC7 (0.52) | CDC7MAPKAPK2PIK3C3PIM1PIM2 | |
| Trifluoroacetic Acid SCHEMBL4996147 | 0.86 | CDC7 (0.52) | CDC7ASIC1MAPKAPK2PIK3C3PIM1 | |
| Trifluoroacetic Acid SCHEMBL4790707 | 0.86 | CDC7 (0.52) | CDC7ASIC1MAPKAPK2PIK3C3HDAC1 | |
| Trifluoroacetic Acid SCHEMBL4715188 | 0.86 | CDC7 (0.52) | CDC7ABL1 | |
| Trifluoroacetic Acid SCHEMBL4713069 | 0.85 | CDC7 (0.51) | CDC7MAPKAPK2PIK3C3PIM1PIM2 | |
| Trifluoroacetic Acid SCHEMBL4999615 | 0.84 | CDC7 (0.55) | CDC7MAPKAPK2PIK3C3PIM1PIM2 | |
| Trifluoroacetic Acid SCHEMBL4712543 | 0.83 | CDC7 (0.48) | CDC7ASIC1MAPKAPK2PIK3C3CDK1 | |
| Trifluoroacetic Acid SCHEMBL4714169 | 0.82 | CDC7 (0.78) | CDC7ASIC1PIK3C3PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080113971-A1 | PYRAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | HANAU CATHLEEN E | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080113971-A1 | PYRAZOLE COMPOUNDS AS PROTEIN KINASE INHIBITORS | MKNK2, MAPKAPK2, MAP3K2 | CDC7 487/4885ASIC1 3865/4885MAPKAPK2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.