SCHEMBL499656

SCHEMBL499656

C=C(C)C(=O)OCCCCCCN(CC)CC

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.66
THRB P10828 1/20 0.49
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
THPO P40225 1/20 0.46
MTOR P42345 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
PMP22 Q01453 1/20 0.45
MAOB P27338 2/20 0.43
PAOX Q6QHF9 1/20 0.39
CHRM2 P08172 2/20 0.39
CHRM4 P08173 2/20 0.39
CHRM1 P11229 2/20 0.39
CHRM3 P20309 2/20 0.39
APOBEC3A P31941 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109797 1.00 TSHR (0.66) TSHRTHRBPOLBAPEX1HTT
SCHEMBL499772 1.00 TSHR (0.66) TSHRTHRBPOLBAPEX1HTT
SCHEMBL10951222 1.00 TSHR (0.66) TSHRTHRBPOLBAPEX1HTT
SCHEMBL499467 1.00 TSHR (0.66) TSHRTHRBPOLBAPEX1HTT
SCHEMBL500171 1.00 TSHR (0.66) TSHRTHRBPOLBAPEX1HTT
SCHEMBL110690 0.98 TSHR (0.62) TSHRTHRBPOLBAPEX1HTT
SCHEMBL346151 0.93 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28499275 0.89 TSHR (0.75) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1336680 0.88 TSHR (0.80) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11223664 0.88 TSHR (0.80) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020198630-A2 WATER COMPATIBLE CATIONIC GRAFT COPOLYMERS AND INK COMPOSITIONS COMPRISING SAME PENN COLOR, INC. (US) 2020-10-01 WO claimed
US-20200308331-A1 WATER COMPATIBLE CATIONIC GRAFT COPOLYMERS AND INK COMPOSITIONS COMPRISING SAME PENN COLOR, INC. 2020-10-01 US claimed
US-5321110-A Thickeners for shampoo, hair conditioners ISP INVESTMENTS INC. (US) 1994-06-14 US claimed
EP-0106193-A2 Liquid skin cleanser composition UNION CARBIDE CORPORATION (US) 1984-04-25 EP claimed
US-3954960-A Hair and similar cosmetic preparations containing a quaternized copolymer of vinyl pyrrolidone GAF CORPORATION (US) 1976-05-04 US claimed
EP-3347446-B1 A STABLE LAUNDRY OR CLEANING COMPOSITION, PROCESS FOR PREPARING THE SAME, AND METHOD OF USE ISP INVESTMENTS LLC (US) 2024-12-11 EP disclosed
US-12096767-B2 Residual disinfectant composition KIMBERLY-CLARK WORLDWIDE, INC. (US) 2024-09-24 US disclosed
US-20230277704-A1 Disinfectant Composition with Rapid Antiviral Efficacy KIMBERLY-CLARK WORLDWIDE, INC. 2023-09-07 US disclosed
EP-3328373-B1 DISINFECTANT COMPOSITION WITH RAPID ANTIVIRAL EFFICACY KIMBERLY CLARK CO (US) 2023-06-07 EP disclosed
EP-3569682-B1 LIQUID HARD SURFACE CLEANING COMPOSITIONS HAVING IMPROVED VISCOSITY PROCTER & GAMBLE (US) 2022-12-07 EP disclosed
US-20220340703-A1 HYBRIDIZED GRAFT COPOLYMERS IN COATING AND INK COMPOSITIONS PENN COLOR, INC. (US) 2022-10-27 US disclosed
WO-2022162221-A1 DETERGENT COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2022-08-04 WO disclosed
US-4314807-A CATIONIC POLYMER, ANIONIC SURFACTANT SHAMPOO L'OREAL (FR) 1982-02-09 US disclosed
US-4308092-A POLYMER IN AQUEOUS SOLUTION ROHM AND HAAS COMPANY (US) 1981-12-29 US disclosed
US-4255308-A A DISPERSION COMPRISING A BINDER OF A METHYL METHACRYLATE POLYMER, A DISPERSANT OF AN ACRYLIC TERPOLYMER, AND A GRAFT POLYMER OF THE TWO; FINISHES FOR CARS AND TRUCKS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-03-10 US disclosed
US-4020192-A AMINO ALKYL AMIDE ACRYLIC POLYMER FUJI XEROX CO., LTD. (JA) 1977-04-26 US disclosed
US-3980769-A ANIONIC AND AMPHOTERIC SURFACTANTS L'OREAL (FR) 1976-09-14 US disclosed
US-3958581-A Cosmetic composition containing a cationic polymer and divalent metal salt for strengthening the hair L'OREAL (FR) 1976-05-25 US disclosed
US-3954588-A Electrocoating process for depositing a corrosion retardant layer on a metal substrate and sequentially electrocoating a cationic film-forming polymer coating E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-05-04 US disclosed
US-3954960-A Hair and similar cosmetic preparations containing a quaternized copolymer of vinyl pyrrolidone GAF CORPORATION (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12096767-B2 Residual disinfectant composition QARS1, EIF2AK2, POLL TSHR 2755/4885THRB 4598/4885POLB 138/4885
US-20230277704-A1 Disinfectant Composition with Rapid Antiviral Efficacy EIF2AK2, APOBEC3A, APOBEC3C TSHR 2150/4885THRB 4223/4885POLB 110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.