Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.64 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.60 |
| ▸ | TUBB | P07437 | 4/20 | 0.60 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.60 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.60 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.60 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.60 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.60 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.60 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.60 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.60 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.60 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.60 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.60 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.60 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.60 |
| ▸ | NQO2 | P16083 | 3/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4994326 | 1.00 | ESR1 (0.64) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL4994318 | 1.00 | ESR1 (0.64) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL4996079 | 0.99 | ESR1 (0.62) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL4996085 | 0.99 | ESR1 (0.62) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL4990744 | 0.91 | ESR1 (0.64) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL4990755 | 0.91 | ESR1 (0.64) | ESR1ESR2TUBB4ATUBBTUBA3C | |
| SCHEMBL4996892 | 0.90 | RECQL (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4996875 | 0.90 | RECQL (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12507433 | 0.90 | RECQL (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9239062 | 0.89 | TUBB4A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371773-B2 | Breast cancer resistance protein (BCRP) inhibitor | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2008-05-13 | — | — | US | claimed |
| US-20060128636-A1 | Breast cancer resistance protein (bcrp) inhibitor | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2006-06-15 | — | — | US | claimed |
| CN-1744892-A | Breast cancer resistance protein (BCRP) inhibitor | YAKULT HONSHA KK (JP) | 2006-03-08 | — | — | CN | claimed |
| EP-1591117-A1 | BREAST CANCER RESISTANCE PROTEIN (BCRP) INHIBITOR | Kabushiki Kaisha Yakult Honsha (JP) | 2005-11-02 | — | — | EP | claimed |
| US-7371773-B2 | Breast cancer resistance protein (BCRP) inhibitor | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2008-05-13 | — | — | US | disclosed |
| US-20060128636-A1 | Breast cancer resistance protein (bcrp) inhibitor | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2006-06-15 | — | — | US | disclosed |
| CN-1744892-A | Breast cancer resistance protein (BCRP) inhibitor | YAKULT HONSHA KK (JP) | 2006-03-08 | — | — | CN | disclosed |
| EP-1591117-A1 | BREAST CANCER RESISTANCE PROTEIN (BCRP) INHIBITOR | Kabushiki Kaisha Yakult Honsha (JP) | 2005-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128636-A1 | Breast cancer resistance protein (bcrp) inhibitor | ABCC1, OSBP, OSBPL3 | ESR1 413/4885ESR2 454/4885TUBB4A 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.