Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.75 |
| ▸ | TUBB | P07437 | 4/20 | 0.75 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.75 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.75 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.75 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.75 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.75 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.75 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.75 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.75 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.75 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.75 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.75 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.75 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.75 |
| ▸ | NQO2 | P16083 | 3/20 | 0.67 |
| ▸ | NQO1 | P15559 | 1/20 | 0.67 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19112243 | 1.00 | TUBB4A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8397007 | 0.91 | NQO2 (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8397009 | 0.91 | NQO2 (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL12507433 | 0.90 | RECQL (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4996875 | 0.90 | RECQL (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4996892 | 0.90 | RECQL (0.67) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4994326 | 0.89 | ESR1 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8398858 | 0.89 | TUBB4A (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4996750 | 0.89 | ESR1 (0.64) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8398862 | 0.89 | TUBB4A (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10239844-B2 | Disubstituted triazole analogs | BIOVENTURES, LLC (US) | 2019-03-26 | — | — | US | disclosed |
| US-20180186756-A1 | DISUBSTITUTED TRIAZOLE ANALOGS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS | 2018-07-05 | — | — | US | disclosed |
| US-9938246-B2 | Disubstituted triazole analogs | BIOVENTURES, LLC (US) | 2018-04-10 | — | — | US | disclosed |
| EP-3125886-A1 | DISUBSTITUTED TRIAZOLE ANALOGS | Board of Trustees of the University of Arkansas (US) | 2017-02-08 | — | — | EP | disclosed |
| US-20170015635-A1 | DISUBSTITUTED TRIAZOLE ANALOGS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2017-01-19 | — | — | US | disclosed |
| WO-2015153635-A1 | DISUBSTITUTED TRIAZOLE ANALOGS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (US) | 2015-10-08 | — | — | WO | disclosed |
| EP-0640586-A1 | STILBENE DERIVATIVE AND STILBENE ANALOG DERIVATIVE, AND USE THEREOF | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170015635-A1 | DISUBSTITUTED TRIAZOLE ANALOGS | MCL1, CYP51A1, TOP2B | TUBB4A 88/4885TUBB 41/4885TUBA3C 116/4885 |
| US-10239844-B2 | Disubstituted triazole analogs | MCL1, CYP51A1, TOP2B | TUBB4A 88/4885TUBB 41/4885TUBA3C 116/4885 |
| US-20180186756-A1 | DISUBSTITUTED TRIAZOLE ANALOGS | MCL1, CYP51A1, TOP2B | TUBB4A 88/4885TUBB 41/4885TUBA3C 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.