Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 5/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177659 | 0.88 | HTR2A (0.54) | HTR2ACA1CA2HRH1CHRM2 | |
| SCHEMBL7574105 | 0.85 | HTR2A (0.61) | HTR2ACA1CA2HRH1CHRM2 | |
| SCHEMBL17022715 | 0.85 | HTR2A (0.61) | HTR2ACA1CA2HRH1CHRM2 | |
| SCHEMBL5353138 | 0.83 | HTR2A (0.64) | HTR2ACA1CA2HRH1CHRM2 | |
| SCHEMBL499897 | 0.78 | HTR2A (0.58) | HTR2ACA1CA2CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL6557729 | 0.78 | HTR2A (0.58) | HTR2ACA1CA2HRH1CHRM2 | |
| SCHEMBL14759063 | 0.77 | HTR2A (0.52) | HTR2ACA1CA2HRH1CHRM2 | |
| SCHEMBL31026220 | 0.77 | HTR2A (0.52) | HTR2ACA1CA2HRH1CHRM2 | |
| SCHEMBL313685 | 0.77 | ACHE (0.55) | HTR2ACA1CA2HRH1CHRM2 | |
| SCHEMBL8993284 | 0.77 | HTR2A (0.52) | HTR2ACA1CA2HRH1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107072206-B | Pesticidal compositions and related methods | 美国陶氏益农公司 | 2020-02-21 | — | — | CN | claimed |
| CN-113382996-B | Theophylline derivatives with nematicidal activity, agronomic compositions and related uses | 高文作物保护公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118318839-A | Use of substituted phenylamide isoxazoline compound for controlling thysanoptera pests | 海利尔药业集团股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118290356-A | Substituted benzil isoxazoline compound and application of preparation containing substituted benzil isoxazoline compound in preventing and controlling harmful mites and reducing reproductive power of harmful mites | 海利尔药业集团股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-117770262-A | Molecules having pesticidal utility and compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-111164077-B | Herbicidal 3-phenyl-5-trifluoromethyl isoxazoline-5-carboxamides of cyclopentylcarboxylic acids and esters thereof | 拜耳公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-111868042-B | Herbicidal 3-phenylisoxazoline-5-carboxamides of cyclopentylcarboxylic acid derivatives | 拜耳公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-112778271-B | Molecules having pesticidal utility and compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-115943143-A | 1-pyrazinylpyrazolyl-3-oxyalkyl acids and derivatives thereof and their use for controlling undesired vegetation | 拜耳公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115667231-A | Substituted isophthalic acid diamides and their use as herbicides | 拜耳公司 | 2023-01-31 | — | — | CN | disclosed |
| EP-1866317-A1 | 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | Pharmacia & Upjohn Company LLC (US) | 2007-12-19 | — | — | EP | disclosed |
| EP-1844052-A1 | THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | Pharmacia & Upjohn Company LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006103544-A2 | 4-PIPERAZINYLTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006103555-A1 | 4-PIPERAZINOTHIENO [2, 3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006103545-A1 | 4-PIPERAZINYLTHIENO [2,3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006100591-A1 | 4-PIPERAZINNYLTHIENO [2,3-D] PYRIMIDINE COMPOUNDS AS PLATELET AGGREGATION INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-09-28 | — | — | WO | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |
| EP-0980375-A4 | SILYLATED AND N-SILYLATED COMPOUND SYNTHESIS | BOULDER SCIENT CO (US) | 2003-01-22 | — | — | EP | disclosed |
| EP-0980375-A1 | N-SILYLATED COMPOUND SYNTHESIS | BOULDER SCIENTIFIC COMPANY (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1999038871-A1 | SILYLATED AND N-SILYLATED COMPOUND SYNTHESIS | BOULDER SCIENTIFIC COMPANY (US) | 1999-08-05 | — | — | WO | disclosed |