Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.52 |
| ▸ | TDO2 | P48775 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315778 | 0.93 | HTR2A (0.50) | HTR2ATDO2HRH1CA1CA2 | |
| SCHEMBL4556626 | 0.91 | HTR2A (0.48) | HTR2ATDO2HRH1CA1CA2 | |
| SCHEMBL30413587 | 0.88 | TDO2 (0.61) | HTR2ATDO2HRH1CA1CA2 | |
| SCHEMBL2231461 | 0.88 | TDO2 (0.61) | HTR2ATDO2HRH1CA1CA2 | |
| SCHEMBL7574105 | 0.85 | HTR2A (0.61) | HTR2ATDO2HRH1CA1CA2 | |
| SCHEMBL17022715 | 0.85 | HTR2A (0.61) | HTR2ATDO2HRH1CA1CA2 | |
| SCHEMBL5353138 | 0.83 | HTR2A (0.64) | HTR2ATDO2HRH1CA1CA2 | |
| SCHEMBL3874745 | 0.81 | HTR2A (0.61) | HTR2ATDO2HRH1JAK2CHRM2 | |
| SCHEMBL8201075 | 0.79 | HTR2A (0.55) | HTR2AHRH1CHRM1ADRA1ADRD3 | |
| SCHEMBL6402895 | 0.79 | MAOA (0.50) | LMNACYP2D6MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519043-A | ANTIINFLAMMATORY AGENTS WITH AMIDE, CARBAMATE OR THIOCARBAMATE GROUPS ON FLUORENE AND BENZENE | SCIOS NOVA INC. (US) | 1996-05-21 | — | — | US | disclosed |